Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 4/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27676401 | 0.86 | ALDH1A1 (0.48) | ALDH1A1ALOX15L3MBTL1GAANPC1 | |
| SCHEMBL6829549 | 0.86 | NOTUM (0.51) | ALDH1A1ALOX15L3MBTL1GAANPC1 | |
| SCHEMBL9178263 | 0.85 | ALDH1A1 (0.50) | ALDH1A1ALOX15L3MBTL1GAANPC1 | |
| SCHEMBL8048603 | 0.85 | ALDH1A1 (0.61) | ALDH1A1ALOX15L3MBTL1NPC1PTPN1 | |
| SCHEMBL6650052 | 0.85 | KMT2A (0.60) | ALDH1A1ALOX15L3MBTL1GAANPC1 | |
| SCHEMBL3084334 | 0.85 | NPC1 (0.68) | ALDH1A1ALOX15GAANPC1NOTUM | |
| SCHEMBL29627850 | 0.84 | NOTUM (0.50) | ALDH1A1ALOX15L3MBTL1GAAPTPN1 | |
| SCHEMBL28691758 | 0.83 | NOTUM (0.49) | ALDH1A1ALOX15L3MBTL1GAAPTPN1 | |
| SCHEMBL1097070 | 0.82 | HTR6 (0.50) | ALDH1A1L3MBTL1NPC1PTPN1NR4A1 | |
| SCHEMBL29467270 | 0.82 | NPC1 (0.68) | ALDH1A1ALOX15L3MBTL1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217350-A1 | BENZOTHIAZOLE AND QUINOLINE DERIVATIVES AND THEIR USE | Shanghai Yao Yuan Biotechnology Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |
| WO-2013175281-A1 | USE OF SUBSTITUTED 2-PHENYL-3H-QUINAZOLIN-4-ONES AND ANALOGS FOR INHIBITING BROMODOMAIN AND EXTRA TERMINAL DOMAIN (BET) PROTEINS | RVX THERAPEUTICS INC. (CA) | 2013-11-28 | — | — | WO | disclosed |