Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 3/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533384 | 0.86 | ALDH1A1 (0.48) | NOTUMALDH1A1ALOX15HRH1CCR3 | |
| SCHEMBL27676401 | 0.86 | ALDH1A1 (0.48) | NOTUMALDH1A1ALOX15HRH1CCR3 | |
| SCHEMBL8048603 | 0.85 | ALDH1A1 (0.61) | ALDH1A1ALOX15ENPP2L3MBTL1NPC1 | |
| SCHEMBL6650052 | 0.85 | KMT2A (0.60) | ALDH1A1ALOX15L3MBTL1GAANPC1 | |
| SCHEMBL29467270 | 0.82 | NPC1 (0.68) | ALDH1A1ALOX15ENPP2L3MBTL1GAA | |
| SCHEMBL2492855 | 0.82 | NPC1 (0.68) | ALDH1A1ALOX15ENPP2L3MBTL1GAA | |
| SCHEMBL6828683 | 0.81 | HRH1 (0.50) | ALDH1A1ALOX15HRH1CCR3KCNH2 | |
| SCHEMBL14528966 | 0.81 | L3MBTL3 (0.59) | L3MBTL1NPC1PTPN1TDP1 | |
| SCHEMBL1664012 | 0.81 | TSHR (0.58) | ALDH1A1ENPP2NPC1MYCTDP1 | |
| SCHEMBL17893580 | 0.81 | ALDH1A1 (0.50) | ALDH1A1ALOX15ENPP2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |