SCHEMBL15533403

SCHEMBL15533403

CC1CCC(C(C)C)C(Oc2ccc(NC(=O)C3CC(C)CCC3C(C)C)cc2)C1

nearest known ligand 0.77

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 4/20 0.77
P2RX4 Q99571 1/20 0.44
EPHX1 P07099 3/20 0.44
TRPV1 Q8NER1 3/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 1/20 0.43
LMNA P02545 1/20 0.43
CYP19A1 P11511 2/20 0.42
SERPINE1 P05121 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acoltremon SCHEMBL29570327 0.87 TRPM8 (1.00) TRPM8EPHX1TRPV1ALDH1A1HPGD
Acoltremon SCHEMBL29225639 0.87 TRPM8 (1.00) TRPM8EPHX1TRPV1ALDH1A1HPGD
Acoltremon SCHEMBL17104729 0.87 TRPM8 (1.00) TRPM8EPHX1TRPV1ALDH1A1HPGD
Acoltremon SCHEMBL23870506 0.87 TRPM8 (1.00) TRPM8EPHX1TRPV1ALDH1A1HPGD
Acoltremon SCHEMBL619824 0.87 TRPM8 (1.00) TRPM8EPHX1TRPV1ALDH1A1HPGD
Acoltremon SCHEMBL23198293 0.87 TRPM8 (1.00) TRPM8EPHX1TRPV1ALDH1A1HPGD
Acoltremon SCHEMBL2575067 0.87 TRPM8 (1.00) TRPM8EPHX1TRPV1ALDH1A1HPGD
Acoltremon SCHEMBL3228667 0.87 TRPM8 (1.00) TRPM8EPHX1TRPV1ALDH1A1HPGD
Acoltremon SCHEMBL14811473 0.87 TRPM8 (1.00) TRPM8EPHX1TRPV1ALDH1A1HPGD
Acoltremon SCHEMBL16227989 0.87 TRPM8 (1.00) TRPM8EPHX1TRPV1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2872109-A2 PERSONAL CARE COMPOSITION COMPRISING A COLLING ACTIVE AND A COPOLYMER COMPRISING ACRYLAMIDOPROPYLTRIMONIUM CHLORIDE Unilever N.V. (NL) 2015-05-20 EP claimed
WO-2013174615-A2 PERSONAL CARE COMPOSITION UNILEVER N.V. (NL) 2013-11-28 WO claimed
US-20250262137-A1 Films and Oral Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2025-08-21 US disclosed
CN-118382423-A Personal care compositions 高露洁-棕榄公司 2024-07-23 CN disclosed
EP-4392005-A1 PERSONAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2024-07-03 EP disclosed
US-20230390164-A1 Films and Oral Care Compositions Comprising Same COLGATE-PALMOLIVE COMPANY (US) 2023-12-07 US disclosed
EP-4199880-A1 FILMS AND ORAL CARE COMPOSITIONS COMPRISING SAME Colgate-Palmolive Company (US) 2023-06-28 EP disclosed
EP-4199889-A1 FILMS AND ORAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2023-06-28 EP disclosed
US-20230181445-A1 Personal Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2023-06-15 US disclosed
WO-2023107659-A1 PERSONAL CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2023-06-15 WO disclosed
CN-116251032-A Personal care compositions 高露洁-棕榄公司 2023-06-13 CN disclosed
WO-2022094212-A1 FILMS AND ORAL CARE COMPOSITIONS COMPRISING SAME COLGATE-PALMOLIVE COMPANY (US) 2022-05-05 WO disclosed
WO-2022094233-A1 FILMS AND ORAL CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2022-05-05 WO disclosed
CN-109010128-B Personal care compositions comprising a cooling active and a copolymer containing acrylamidopropyltrimethylammonium chloride 联合利华知识产权控股有限公司 2021-12-21 CN disclosed
US-10463597-B2 Personal care composition CONOPCO, INC. (US) 2019-11-05 US disclosed
EP-2872109-B1 PERSONAL CARE COMPOSITION COMPRISING A COOLING ACTIVE AND A COPOLYMER COMPRISING ACRYLAMIDOPROPYLTRIMONIUM CHLORIDE UNILEVER NV (NL) 2017-06-14 EP disclosed
EP-2872109-A2 PERSONAL CARE COMPOSITION COMPRISING A COLLING ACTIVE AND A COPOLYMER COMPRISING ACRYLAMIDOPROPYLTRIMONIUM CHLORIDE Unilever N.V. (NL) 2015-05-20 EP disclosed
US-20150110728-A1 PERSONAL CARE COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2015-04-23 US disclosed
WO-2013174615-A2 PERSONAL CARE COMPOSITION UNILEVER N.V. (NL) 2013-11-28 WO disclosed