Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 1.00 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acoltremon SCHEMBL29570327 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL29225639 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL2575067 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL619824 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL23870506 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL23198293 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL14811473 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL17104729 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL16227989 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| SCHEMBL2628780 | 0.88 | TRPM8 (0.78) | TRPM8TRPV1KMT2AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240165004-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2024-05-23 | — | — | US | claimed |
| EP-4304550-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2024-01-17 | — | — | EP | claimed |
| WO-2022189383-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2022-09-15 | — | — | WO | claimed |
| EP-2318356-B1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | PROCTER & GAMBLE (US) | 2015-03-11 | — | — | EP | claimed |
| US-8426643-B2 | Synthesis of cyclohexane derivatives useful as sensates in consumer products | THE PROCTER & GAMBLE COMPANY (US) | 2013-04-23 | — | — | US | claimed |
| US-20100076080-A1 | Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products | THE PROCTER & GAMBLE COMPANY | 2010-03-25 | — | — | US | claimed |
| US-20240165004-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2024-05-23 | — | — | US | disclosed |
| EP-4304550-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022189383-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2022-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240165004-A1 | ORGANIC COMPOUNDS | TAS2R8, TAS2R10, TAS2R20 | TRPM8 58/4885TRPV1 83/4885MEN1 3178/4885 |
| US-20100076080-A1 | Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products | NISCH, TRPM4, TRPM8 | TRPM8 3/4885TRPV1 12/4885MEN1 1170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.