Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 1.00 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acoltremon SCHEMBL29570327 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL29225639 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL2575067 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL23870506 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL3228667 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL23198293 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL14811473 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL17104729 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| Acoltremon SCHEMBL16227989 | 1.00 | TRPM8 (1.00) | TRPM8TRPV1MEN1KMT2ANPC1 | |
| SCHEMBL2628780 | 0.88 | TRPM8 (0.78) | TRPM8TRPV1KMT2AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 637 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12397518-B2 | WS12-releasing contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2025-08-26 | — | — | US | claimed |
| WO-2025068299-A1 | AEROSOL-GENERATING ARTICLE, DEVICE AND SYSTEM | JT INTERNATIONAL SA (CH) | 2025-04-03 | — | — | WO | claimed |
| CN-117099025-B | WS12 releasing contact lens | 库博光学国际有限公司 | 2025-03-11 | — | — | CN | claimed |
| EP-4288813-B1 | WS12-RELEASING CONTACT LENS | COOPERVISION INT LTD (GB) | 2024-09-04 | — | — | EP | claimed |
| EP-4407354-A2 | WS12-RELEASING CONTACT LENS | CooperVision International Limited (GB) | 2024-07-31 | — | — | EP | claimed |
| CN-118076340-A | Ophthalmic pharmaceutical composition and use thereof | 爱瑞制药公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117752549-A | Oral care compositions containing bioactive enzymes and uses thereof | 北京心悦创造科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| US-11934044-B2 | WS12-releasing contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2024-03-19 | — | — | US | claimed |
| CN-117582380-A | Oral care composition, application thereof and toothpaste | 北京心悦创造科技有限公司 | 2024-02-23 | — | — | CN | claimed |
| US-20240036354-A1 | WS12-RELEASING CONTACT LENS | COOPERVISION INTERNATIONAL LIMITED (GB) | 2024-02-01 | — | — | US | claimed |
| US-20140134113-A1 | PHARMACEUTICAL COMPOSITIONS | SYMRISE AG (DE) | 2014-05-15 | — | — | US | claimed |
| EP-2730280-A1 | A pharmaceutical composition comprising a menthane carboxylic acid amide | Symrise AG (DE) | 2014-05-14 | — | — | EP | claimed |
| WO-2013164706-A1 | SMOKING ARTICLE MOUTHPIECE WITH COOLING AGENT INCLUSION COMPLEX | PHILIP MORRIS PRODUCTS S.A. (CH) | 2013-11-07 | — | — | WO | claimed |
| US-20130156885-A1 | CHEWING GUM CONTAINING COMBINATIONS OF PHYSIOLOGICAL COOLING AGENTS | WM. WRIGLEY JR. COMPANY | 2013-06-20 | — | — | US | claimed |
| US-20110081303-A1 | TEETH CLEANING COMPOUND CONTAINING MENTHOL WITH REDUCED BITTER SENSATION | SYMRISE AG (DE) | 2011-04-07 | — | — | US | claimed |
| US-7893072-B2 | Cool-genic compounds as anticarcinogenic agents promoting apoptosis and inhibit angiogenesis; antiproliferative agents | GENENTECH, INC. (US) | 2011-02-22 | — | — | US | claimed |
| WO-2009027331-A2 | TIPPING PAPER | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2009-03-05 | — | — | WO | claimed |
| WO-2008138162-A1 | COMPOSITIONS AND THEIR USE | GIVAUDAN SA (CH) | 2008-11-20 | — | — | WO | claimed |
| US-20070233026-A1 | Absorbent articles with feedback signal upon urination | THE PROCTER & GAMBLE COMPANY | 2007-10-04 | — | — | US | claimed |
| US-20050090514-A1 | Trp-p8 active compounds and therapeutic treatment methods | GENENTECH, INC. | 2005-04-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090514-A1 | Trp-p8 active compounds and therapeutic treatment methods | TSG101, TP53, BAX | TRPM8 28/4885TRPV1 14/4885MEN1 3338/4885 |
| US-20110081303-A1 | TEETH CLEANING COMPOUND CONTAINING MENTHOL WITH REDUCED BITTER SENSATION | TAS2R10, TAS2R30, TAS2R14 | TRPM8 45/4885TRPV1 93/4885MEN1 2898/4885 |
| US-20140134113-A1 | PHARMACEUTICAL COMPOSITIONS | CYP2C19, CYP3A7, CYP3A4 | TRPM8 109/4885TRPV1 346/4885MEN1 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.