Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.46 |
| ▸ | BCR | P11274 | 3/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.43 |
| ▸ | FAAH | O00519 | 8/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15534389 | 0.90 | ABL1 (0.39) | ABL1BCRTRPV1FAAHCYP1A2 | |
| SCHEMBL15533688 | 0.85 | TRPV1 (0.50) | ABL1BCRTRPV1FAAHCYP1A2 | |
| SCHEMBL15533699 | 0.80 | CCNB2 (0.43) | ABL1BCRCLK4 | |
| SCHEMBL15533597 | 0.79 | TRPV1 (0.46) | ABL1BCRTRPV1FAAHCYP1A2 | |
| SCHEMBL15534053 | 0.76 | ABL1 (0.50) | ABL1BCRTRPV1FAAH | |
| SCHEMBL15534555 | 0.75 | ABL1 (0.49) | ABL1BCRTRPV1FAAH | |
| SCHEMBL15535216 | 0.75 | MAPT (0.49) | ABL1BCRTRPV1CYP1A2CYP3A4 | |
| SCHEMBL15534046 | 0.75 | ABL1 (0.68) | ABL1BCRTRPV1FAAHCYP1A2 | |
| SCHEMBL15533974 | 0.74 | ABL1 (0.69) | ABL1BCRTRPV1CYP1A2CYP3A4 | |
| SCHEMBL15534101 | 0.73 | TRPV1 (0.47) | ABL1BCRTRPV1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | disclosed |