Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 16/20 | 0.69 |
| ▸ | BCR | P11274 | 15/20 | 0.69 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533765 | 0.90 | ABL1 (0.57) | ABL1BCRMAPK1TP53MEN1 | |
| SCHEMBL15534046 | 0.84 | ABL1 (0.68) | ABL1BCRTRPV1MAPK1TP53 | |
| SCHEMBL12943132 | 0.81 | ABL1 (1.00) | ABL1BCRTRPV1MAPK1TP53 | |
| SCHEMBL15534101 | 0.80 | TRPV1 (0.47) | ABL1BCRTRPV1MAPK1TP53 | |
| SCHEMBL5801083 | 0.79 | TRPV1 (0.69) | ABL1BCRTRPV1MAPK1TP53 | |
| Hydrochloric Acid SCHEMBL15533549 | 0.79 | TRPV1 (0.47) | ABL1BCRTRPV1MAPK1TP53 | |
| Bromide SCHEMBL15534396 | 0.79 | TRPV1 (0.47) | ABL1BCRTRPV1MAPK1TP53 | |
| SCHEMBL15533814 | 0.79 | ABL1 (0.59) | ABL1BCRTRPV1TP53MAPT | |
| SCHEMBL15533252 | 0.78 | DKK1 (0.47) | ABL1BCRCLK4 | |
| SCHEMBL15534555 | 0.77 | ABL1 (0.49) | ABL1BCRTRPV1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | disclosed |