Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 3/20 | 0.41 |
| ▸ | CLK1 | P49759 | 2/20 | 0.41 |
| ▸ | CLK2 | P49760 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533101 | 0.86 | CCNB2 (0.55) | CCNB2CDK1RETCCNB1CCNB3 | |
| SCHEMBL15533704 | 0.81 | ABL1 (0.47) | ABL1DYRK1ACLK4CDK2KDM4E | |
| SCHEMBL15533263 | 0.81 | CLK1 (0.64) | CLK1CLK2DYRK1ACLK4DYRK1B | |
| SCHEMBL15534142 | 0.80 | ABL1 (0.46) | ABL1CLK4BCR | |
| SCHEMBL15534289 | 0.79 | SYK (0.59) | CLK1CLK2DYRK1ACLK4DYRK1B | |
| SCHEMBL15533252 | 0.78 | DKK1 (0.47) | ABL1CLK1CLK2DYRK1ACLK4 | |
| SCHEMBL15534056 | 0.78 | MEN1 (0.46) | CCNB2CDK1RETCCNB1CCNB3 | |
| SCHEMBL15533886 | 0.76 | CLK1 (0.67) | CLK1CLK2DYRK1ACLK4DYRK1B | |
| SCHEMBL15534348 | 0.76 | MEN1 (0.46) | CLK1CLK2DYRK1ACLK4DYRK1B | |
| SCHEMBL15534057 | 0.75 | CLK1 (0.47) | CLK1CLK2DYRK1ACLK4DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | claimed |
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | disclosed |