SCHEMBL15534154

SCHEMBL15534154

C=C(C)C(=O)OC([SiH3])(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9841926 0.78 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL1679798 0.78 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL3061533 0.78 ALDH1A1 (0.33) ALDH1A1
SCHEMBL27971688 0.78 TSHR (0.33) ALDH1A1TSHR
SCHEMBL29074260 0.77 ALDH1A1 (0.48) ALDH1A1TSHR
SCHEMBL10790001 0.74 ALDH1A1 (0.31) ALDH1A1
SCHEMBL393525 0.72 TSHR (0.40) ALDH1A1TSHR
SCHEMBL25430922 0.72 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL14675514 0.71 TSHR (0.35) ALDH1A1TSHR
SCHEMBL11822907 0.71 ALDH1A1 (0.33) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2856218-A1 FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS Bausch & Lomb Incorporated (US) 2015-04-08 EP disclosed
WO-2013177008-A1 FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS BAUSCH & LOMB INCORPORATED (US) 2013-11-28 WO disclosed