SCHEMBL393525

SCHEMBL393525

C=C(C)C(=O)OCC([SiH3])(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
ALDH1A1 P00352 2/20 0.40
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396936 0.83 THRB (0.43) TSHRALDH1A1THRB
SCHEMBL5783939 0.81 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL35614 0.80 TSHR (0.47) TSHRALDH1A1THRB
SCHEMBL396763 0.79 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL396293 0.79 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL29011415 0.78 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL1679798 0.77 ALDH1A1 (0.33) TSHRALDH1A1THRB
SCHEMBL9841926 0.77 ALDH1A1 (0.33) TSHRALDH1A1THRB
SCHEMBL580728 0.76 THRB (0.47) TSHRALDH1A1THRB
SCHEMBL397011 0.75 ALDH1A1 (0.47) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600820-B2 Photocurable composition with high silicon content CANON KABUSHIKI KAISHA (JP) 2026-04-14 US claimed
US-20250368802-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT AND HIGH STABILITY CANON KK (JP) 2025-12-04 US claimed
US-20240199816-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT CANON KABUSHIKI KAISHA (JP) 2024-06-20 US claimed
WO-2024123531-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT CANON KABUSHIKI KAISHA (JP) 2024-06-13 WO claimed
EP-1945231-B1 CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL ROCHAL PARTNERS LLP (US) 2021-11-10 EP claimed
EP-2764065-B1 SACRIFICIAL ADHESIVE COATINGS ROCHAL IND LLC (US) 2017-03-22 EP claimed
EP-1898264-B1 Toner compositions XEROX CORP (US) 2016-04-06 EP claimed
US-8969429-B2 Low-tack, hydrophobic ophthalmic device materials NOVARTIS AG (CH) 2015-03-03 US claimed
EP-2673666-B1 LOW-TACK, HYDROPHOBIC OPHTHALMIC DEVICE MATERIALS NOVARTIS AG (CH) 2014-12-31 EP claimed
EP-2764065-A1 SACRIFICIAL ADHESIVE COATINGS Rochal Industries, LLP (US) 2014-08-13 EP claimed
WO-2013052276-A1 SACRIFICIAL ADHESIVE COATINGS ROCHAL INDUSTRIES, LLP (US) 2013-04-11 WO claimed
US-8263720-B1 Sacrificial adhesive coatings ROCHAL INDUSTRIES, LLP (US) 2012-09-11 US claimed
WO-2012109228-A1 LOW-TACK, HYDROPHOBIC OPHTHALMIC DEVICE MATERIALS NOVARTIS AG (CH) 2012-08-16 WO claimed
US-20120202916-A1 Low-Tack, Hydrophobic Ophthalmic Device Materials NOVARTIS AG (CH) 2012-08-09 US claimed
US-8197803-B2 Method of forming a conformable solvent-based bandage and coating material ROCHAL INDUSTRIES, LLP (US) 2012-06-12 US claimed
US-20120114729-A1 SILICONE-PEROXIDE COMPOSITIONS FOR LONG-TERM, CONTROLLED OXYGEN RELEASE UNIVERSITY OF MIAMI (US) 2012-05-10 US claimed
US-8142970-B2 Toner compositions XEROX CORPORATION (US) 2012-03-27 US claimed
WO-2010121024-A2 SILICONE-PEROXIDE COMPOSITIONS FOR LONG-TERM, CONTROLLED OXYGEN RELEASE UNIVERSITY OF MIAMI (US) 2010-10-21 WO claimed
US-20090210002-A1 METHOD OF FORMING A CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL ROCHAL INDUSTRIES LLP (US) 2009-08-20 US claimed
US-20070041935-A1 Polymerizable cyanoacrylate monomer and volatile liquid selected from linear and cyclic siloxanes, polydimethylsiloxanes, isooctane, and octane; kits ROCHAL PARTNERS LLP 2007-02-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600820-B2 Photocurable composition with high silicon content BIRC2, ACP1, IRS1 TSHR 4173/4885ALDH1A1 3351/4885THRB 4666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.