Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9841926 | 0.86 | ALDH1A1 (0.33) | ALDH1A1THRBTSHR | |
| SCHEMBL15534154 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL393525 | 0.77 | TSHR (0.40) | ALDH1A1THRBTSHR | |
| SCHEMBL8462716 | 0.76 | ALDH1A1 (0.33) | ALDH1A1THRBTSHR | |
| SCHEMBL396936 | 0.75 | THRB (0.43) | ALDH1A1THRBTSHR | |
| SCHEMBL27618040 | 0.73 | THRB (0.32) | ALDH1A1THRBTSHR | |
| SCHEMBL3061533 | 0.72 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL4443942 | 0.72 | — | — | |
| SCHEMBL35614 | 0.72 | TSHR (0.47) | ALDH1A1THRBTSHR | |
| SCHEMBL29850911 | 0.72 | TSHR (0.36) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307189-A1 | SILICONE HYDROGEL CONTACT LENSES WITH CONVERTIBLE COMFORT AGENTS | Novartis AG (CH) | 2011-04-13 | — | — | EP | claimed |
| WO-2010011492-A1 | SILICONE HYDROGEL CONTACT LENSES WITH CONVERTIBLE COMFORT AGENTS | NOVARTIS AG (CH) | 2010-01-28 | — | — | WO | claimed |
| CN-112831050-B | Single-end-capped organic siloxane macromonomer, silicon hydrogel, corneal contact lens and preparation method | 江苏海伦隐形眼镜有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-111328381-B | Method for manufacturing ophthalmic lens with embedded component | 株式会社实瞳 | 2021-08-24 | — | — | CN | disclosed |
| CN-111328381-A | Method for manufacturing ophthalmic lens with embedded component | 株式会社实瞳 | 2020-06-23 | — | — | CN | disclosed |
| EP-2124819-A2 | PROCESS FOR THE MANUFACTURE OF A COMPOSITE MATERIAL | Novartis Ag (CH) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008107448-A2 | PROCESS FOR THE MANUFACTURE OF A COMPOSITE MATERIAL | NOVARTIS AG (CH) | 2008-09-12 | — | — | WO | disclosed |
| WO-2002072166-A1 | COMPOSITIONS FOR DRUG DELIVERY | BIOCURE, INC. (US) | 2002-09-19 | — | — | WO | disclosed |
| WO-1993023773-A1 | PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL | CIBA-GEIGY AG (CH) | 1993-11-25 | — | — | WO | disclosed |