Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL601374 | 0.87 | TSHR (0.50) | TSHRLMNACYP3A4ALOX15HPGD | |
| SCHEMBL31015497 | 0.84 | TSHR (0.48) | TSHRLMNACYP3A4ALOX15HPGD | |
| SCHEMBL27224387 | 0.84 | TSHR (0.48) | TSHRLMNACYP3A4ALOX15HPGD | |
| SCHEMBL344702 | 0.84 | TSHR (0.48) | TSHRLMNACYP3A4ALOX15HPGD | |
| SCHEMBL345474 | 0.84 | TSHR (0.48) | TSHRLMNACYP3A4ALOX15HPGD | |
| SCHEMBL345063 | 0.84 | LMNA (0.48) | TSHRLMNACYP3A4HPGDESR1 | |
| SCHEMBL232482 | 0.79 | CA2 (0.55) | FDPSTSHRLMNAMEN1KMT2A | |
| SCHEMBL1491759 | 0.79 | MEN1 (0.44) | FDPSTSHRLMNAMEN1KMT2A | |
| SCHEMBL13713762 | 0.79 | CA2 (0.55) | TSHRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL141747 | 0.79 | HPGD (0.59) | FDPSTSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852593-A1 | SUBSTITUTED PYRROLOPYRIMIDINES | Bayer Pharma Aktiengesellschaft (DE) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013174743-A1 | SUBSTITUTED PYRROLOPYRIMIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2013-11-28 | — | — | WO | disclosed |