Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.36 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5664202 | 0.97 | MAPT (0.42) | MEN1MAPTKMT2AACHEHPGD | |
| SCHEMBL141747 | 0.83 | HPGD (0.59) | MEN1MAPTKMT2AACHEHPGD | |
| SCHEMBL15534249 | 0.79 | FDPS (0.42) | MEN1MAPTKMT2AACHEHPGD | |
| SCHEMBL3289719 | 0.77 | CYP3A4 (0.50) | MEN1MAPTKMT2AACHECYP3A4 | |
| SCHEMBL24899757 | 0.74 | HPGD (0.42) | HPGDTSHRLMNACA1CA2 | |
| SCHEMBL3888438 | 0.74 | HPGD (0.70) | MEN1MAPTKMT2AACHEHPGD | |
| SCHEMBL11232452 | 0.74 | TYR (0.44) | MEN1MAPTKMT2AHPGDALDH1A1 | |
| SCHEMBL22348417 | 0.73 | MAP4K4 (0.42) | MAPTCYP3A4TDP1ALDH1A1TP53 | |
| SCHEMBL22352641 | 0.73 | MAOA (0.55) | MEN1CYP3A4CA12CA1CA2 | |
| SCHEMBL21313336 | 0.72 | ALDH1A1 (0.36) | CYP3A4ALDH1A1TSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026103887-A1 | PROLINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 北京康辰药业股份有限公司 | 2026-05-21 | — | — | WO | disclosed |
| EP-4676602-A1 | COMPOUNDS TARGETING MUTATIONS IN P53 AND USES THEREOF | Merck Sharp & Dohme LLC (US) | 2026-01-14 | — | — | EP | disclosed |
| WO-2025092989-A1 | SUBSTITUTED QUINAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMBINATION THEREOF, AND USE THEREOF | 泰州红云制药有限公司 | 2025-05-08 | — | — | WO | disclosed |
| WO-2024240242-A1 | COMPOUND CONTAINING AMIDE-SUBSTITUTED AROMATIC RING, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 正大天晴药业集团股份有限公司 | 2024-11-28 | — | — | WO | disclosed |
| EP-2300013-B2 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | TAKEDA PHARMACEUTICALS CO (JP) | 2024-11-13 | — | — | EP | disclosed |
| WO-2024187153-A1 | COMPOUNDS TARGETING MUTATIONS IN P53 AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2024-09-12 | — | — | WO | disclosed |
| CN-114315899-B | 3- (Aromatic ring imidazole) pyrazolopyrimidine derivative and application thereof | 上海美迪西生物医药股份有限公司 | 2024-09-03 | — | — | CN | disclosed |
| WO-2022213975-A1 | COMPOUNDS TARGETING Y220C MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-10-13 | — | — | WO | disclosed |
| CN-114315899-A | 3- (aromatic benzimidazolyl) pyrazolopyrimidine derivative and application thereof | 上海美迪西生物医药股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-112004790-A | Novel indoleamine 2, 3-dioxygenase inhibitor and preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2020-11-27 | — | — | CN | disclosed |
| US-20080255155-A1 | KINASE INHIBITORS AND USES THEREOF | METHLYGENE INC. (CA) | 2008-10-16 | — | — | US | disclosed |
| EP-1940843-A2 | UNSATURATED HETEROCYCLIC DERIVATIVES | ARIAD PHARMACEUTICALS, INC. (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2008046216-A1 | KINASE INHIBITORS AND USES THEREOF | METHYLGENE, INC. (CA) | 2008-04-24 | — | — | WO | disclosed |
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | GILEAD SCIENCES, INC. | 2008-03-27 | — | — | US | disclosed |
| WO-2007021937-A2 | UNSATURATED HETEROCYCLIC DERIVATIVES | ARIAD PHARMACEUTICALS, INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| EP-1487459-A4 | PEPTIDE ANALOGUES AND USES THEREOF | ARIAD PHARMA INC (US) | 2006-05-24 | — | — | EP | disclosed |
| US-20050065171-A1 | Substituted purine derivatives | ARIAD PHARMACEUTICALS, INC. | 2005-03-24 | — | — | US | disclosed |
| EP-1487459-A1 | PEPTIDE ANALOGUES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003077928-A1 | PEPTIDE ANALOGUES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2003-09-25 | — | — | WO | disclosed |
| WO-2003077928-A1 | PEPTIDE ANALOGUES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065171-A1 | Substituted purine derivatives | ADORA2A, PNP, HPRT1 | MEN1 3230/4885MAPT 4360/4885KMT2A 2802/4885 |
| US-20080255155-A1 | KINASE INHIBITORS AND USES THEREOF | ABL1, MAP3K20, MAP3K1 | MEN1 1165/4885MAPT 1229/4885KMT2A 811/4885 |
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | TYMP, PNP, PIKFYVE | MEN1 4347/4885MAPT 2025/4885KMT2A 1777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.