Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735708 | 0.87 | — | — | |
| SCHEMBL2099496 | 0.87 | — | — | |
| SCHEMBL2099639 | 0.87 | — | — | |
| SCHEMBL9374563 | 0.87 | SIGMAR1 (0.46) | SIGMAR1CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL15760641 | 0.85 | SIGMAR1 (0.49) | SIGMAR1CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL10130235 | 0.81 | GNAI3 (0.46) | SIGMAR1 | |
| SCHEMBL10130223 | 0.81 | GNAI3 (0.46) | SIGMAR1 | |
| SCHEMBL76763 | 0.81 | GNAI3 (0.46) | SIGMAR1 | |
| SCHEMBL24582593 | 0.79 | SIGMAR1 (0.41) | SIGMAR1CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL20082498 | 0.79 | KEAP1 (0.42) | SIGMAR1CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010433-A1 | CHEMILUMINESCENT COMPOUNDS FOR MULTIPLEXING | Abbott Laboratories (US) | 2022-06-15 | — | — | EP | disclosed |
| EP-4010707-A1 | METHODS FOR DETECTING ASSAY INTERFERENTS AND INCREASING DYNAMIC RANGE | Abbott Laboratories (US) | 2022-06-15 | — | — | EP | disclosed |
| WO-2021026403-A1 | METHODS FOR DETECTING ASSAY INTERFERENTS AND INCREASING DYNAMIC RANGE | ABBOTT LABORATORIES (US) | 2021-02-11 | — | — | WO | disclosed |
| WO-2021026402-A1 | CHEMILUMINESCENT COMPOUNDS FOR MULTIPLEXING | ABBOTT LABORATORIES (US) | 2021-02-11 | — | — | WO | disclosed |
| EP-3313846-A1 | THIENOPYRROLE COMPOUNDS AND USES THEREOF AS INHIBITORS OF OPLOPHORUS-DERIVED LUCIFERASES | Promega Corporation (US) | 2018-05-02 | — | — | EP | disclosed |
| WO-2016210294-A1 | THIENOPYRROLE COMPOUNDS AND USES THEREOF AS INHIBITORS OF OPLOPHORUS-DERIVED LUCIFERASES | PROMEGA CORPORATION (US) | 2016-12-29 | — | — | WO | disclosed |
| WO-2013177510-A1 | NEURONAL NICOTINIC RECEPTOR AGONISTS FOR TREATING SCHIZOPHRENIA IN PATIENTS WITH VARIANTS OF COMT GENE | ABBVIE INC. (US) | 2013-11-28 | — | — | WO | disclosed |
| WO-2013177498-A1 | AGONISTS OF NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR A7 SUBTYPE FOR USE IN THE TREATMENT OF COGNITIVE SYMPTOMS OF SCHIZOPHRENIA | ABBVIE INC. (US) | 2013-11-28 | — | — | WO | disclosed |