Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | PRKCG | P05129 | 1/20 | 0.45 |
| ▸ | PRKCB | P05771 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533961 | 0.86 | CAMKK2 (0.53) | MAPTALDH1A1GAADYRK1ACLK4 | |
| SCHEMBL15533662 | 0.81 | CYP2C19 (0.47) | MAPTALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL15534056 | 0.81 | MEN1 (0.46) | MAPTALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL15533704 | 0.80 | ABL1 (0.47) | MAPTALDH1A1DYRK1ACLK4KDM4E | |
| SCHEMBL15533865 | 0.79 | SYK (0.53) | MAPTSMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL15534241 | 0.78 | CLK1 (0.63) | MAPTDYRK1ACLK4JAK2FLT3 | |
| SCHEMBL15533965 | 0.78 | SYK (0.51) | MAPTALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL15533545 | 0.78 | DYRK1A (0.49) | MAPTALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL15534400 | 0.77 | CLK1 (0.65) | MAPTALDH1A1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL4903233 | 0.77 | JAK2 (0.65) | MEN1NPC1RAB9AKMT2ADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | claimed |
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | disclosed |