Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.47 |
| ▸ | BCR | P11274 | 5/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 2/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | PRKCB | P05771 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PRKCH | P24723 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 4/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533961 | 0.87 | CAMKK2 (0.53) | DYRK1ACLK4PIK3CGCAMKK2JAK2 | |
| SCHEMBL15533699 | 0.81 | CCNB2 (0.43) | ABL1BCRDYRK1ACLK4PRKCA | |
| SCHEMBL15533865 | 0.80 | SYK (0.53) | ABL1BCRDYRK1ACLK4PRKCA | |
| SCHEMBL15534009 | 0.80 | MAPT (0.48) | DYRK1ACLK4PRKCAPRKD3PRKCG | |
| SCHEMBL15535232 | 0.80 | MAPT (0.47) | ABL1BCRDYRK1ACLK4PRKCA | |
| SCHEMBL15533263 | 0.78 | CLK1 (0.64) | DYRK1ACLK4CDK2ULK1MAPT | |
| SCHEMBL15534241 | 0.77 | CLK1 (0.63) | ABL1BCRDYRK1ACLK4PIK3CG | |
| SCHEMBL15533684 | 0.77 | DYRK1A (0.47) | ABL1BCRDYRK1ACLK4PRKCA | |
| SCHEMBL15533545 | 0.77 | DYRK1A (0.49) | ABL1BCRDYRK1ACLK4ZAP70 | |
| SCHEMBL4903233 | 0.76 | JAK2 (0.65) | ABL1BCRDYRK1ACLK4PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | claimed |