SCHEMBL1553636

SCHEMBL1553636

OCCc1ncncc1F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TKT P29401 1/20 0.32
MAP2K1 Q02750 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28472626 0.83
SCHEMBL16279688 0.74
SCHEMBL29618892 0.74
SCHEMBL371953 0.74
SCHEMBL27654856 0.72 CYP11B1 (0.40)
SCHEMBL4973249 0.71 AGBL2 (0.41)
Fluoxidine SCHEMBL784774 0.70
Fluoxidine SCHEMBL30871916 0.70
SCHEMBL1554478 0.69 ERN1 (0.31)
SCHEMBL1554936 0.68 ALDH1A1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011045807-A2 A NOVEL PROCESS TO MANUFACTURE (2R,3S)-2-(2,4-DIFLUOROPHENYL)-3-(5-FLUOROPYRIMIDIN-4-YL)-1-(1H-1,2,4-TRIAZOL-1-YL)BUTAN-2-OL NEULAND LABORATORIES LTD. (IN) 2011-04-21 WO claimed
WO-2011045807-A2 A NOVEL PROCESS TO MANUFACTURE (2R,3S)-2-(2,4-DIFLUOROPHENYL)-3-(5-FLUOROPYRIMIDIN-4-YL)-1-(1H-1,2,4-TRIAZOL-1-YL)BUTAN-2-OL NEULAND LABORATORIES LTD. (IN) 2011-04-21 WO disclosed