Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 8/20 | 0.48 |
| ▸ | OSBP | P22059 | 1/20 | 0.46 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.46 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 2/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | GC | P02774 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15536784 | 1.00 | VDR (0.48) | VDROSBPOSBP2INPP5DCDC25A | |
| SCHEMBL5406429 | 0.88 | INPP5D (0.47) | INPP5DCDC25ACDC25B | |
| SCHEMBL6706039 | 0.85 | CDC25A (0.49) | OSBPINPP5DCDC25ACDC25B | |
| SCHEMBL17825552 | 0.84 | PTPN1 (0.45) | INPP5DCDC25ACDC25B | |
| SCHEMBL29406465 | 0.84 | OSBP (0.55) | VDROSBPOSBP2MAPTSMN1; SMN2 | |
| SCHEMBL29402650 | 0.84 | OSBP (0.55) | VDROSBPOSBP2MAPTSMN1; SMN2 | |
| SCHEMBL28479084 | 0.84 | OSBP (0.55) | VDROSBPOSBP2MAPTSMN1; SMN2 | |
| SCHEMBL3225451 | 0.83 | CDC25A (0.41) | INPP5DCDC25ACDC25B | |
| SCHEMBL11524136 | 0.77 | OSBP (0.75) | VDROSBPOSBP2INPP5DCDC25A | |
| SCHEMBL11571094 | 0.77 | OSBP (0.75) | VDROSBPOSBP2INPP5DCDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855430-A1 | CRYSTALLIZATION OF (20R,22R)-2-METHYLENE-19-NOR-22-METHYL-1alpha ,25-DIHYDROXYVITAMIN D3 AND RELATED PRECURSORS | Wisconsin Alumni Research Foundation (US) | 2015-04-08 | — | — | EP | claimed |
| WO-2013180881-A1 | CRYSTALLIZATION OF (20R,22R)-2-METHYLENE-19-NOR-22-METHYL-1α,25-DIHYDROXYVITAMIN D3 AND RELATED PRECURSORS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-12-05 | — | — | WO | claimed |