Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPP5D | Q92835 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 9/20 | 0.46 |
| ▸ | CDC25B | P30305 | 9/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15536784 | 0.88 | VDR (0.48) | INPP5DCDC25ACDC25B | |
| SCHEMBL6706039 | 0.88 | CDC25A (0.49) | INPP5DCDC25ACDC25BGPBAR1AKR1B10 | |
| SCHEMBL15536787 | 0.88 | VDR (0.48) | INPP5DCDC25ACDC25B | |
| SCHEMBL17825552 | 0.87 | PTPN1 (0.45) | INPP5DCDC25ACDC25BGPBAR1AKR1B10 | |
| SCHEMBL3225451 | 0.85 | CDC25A (0.41) | INPP5DCDC25ACDC25BGPBAR1AKR1B10 | |
| SCHEMBL3225968 | 0.79 | PTPN1 (0.46) | INPP5DCDC25ACDC25BGPBAR1AKR1B10 | |
| SCHEMBL9390498 | 0.76 | GPBAR1 (0.38) | INPP5DCDC25ACDC25BGPBAR1AKR1B10 | |
| SCHEMBL6560622 | 0.76 | INPP5D (0.62) | INPP5DCDC25ACDC25BGPBAR1MEN1 | |
| SCHEMBL6560618 | 0.76 | INPP5D (0.62) | INPP5DCDC25ACDC25BGPBAR1MEN1 | |
| SCHEMBL25711251 | 0.74 | USP2 (0.56) | INPP5DCDC25ACDC25BGPBAR1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241749-B2 | 2α-Methyl and 2β-methyl analogs of 19,26,27-trinor-(20S)-1α-hydroxyvitamin D3 and their uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-20060116352-A1 | 2alpha-Methyl and 2beta-methyl analogs of 19,26,27-trinor-(20S)-1alpha-hydroxyvitamin D3 and their uses | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2006-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116352-A1 | 2alpha-Methyl and 2beta-methyl analogs of 19,26,27-trinor-(20S)-1alpha-hydroxyvitamin D3 and their uses | CYP24A1, CYP27B1, CD14 | INPP5D 1856/4885CDC25A 399/4885CDC25B 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.