SCHEMBL1553692

SCHEMBL1553692

CC(C)(Br)C(=O)c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.61
ALDH1A1 P00352 1/20 0.61
L3MBTL1 Q9Y468 2/20 0.48
LMNA P02545 1/20 0.48
MMP2 P08253 2/20 0.41
MMP13 P45452 2/20 0.41
MMP1 P03956 1/20 0.41
EZH2 Q15910 1/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
MAPT P10636 2/20 0.40
GAA P10253 1/20 0.40
CTSK P43235 1/20 0.40
CES1 P23141 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CHRNA7 P36544 1/20 0.38
MGLL Q99685 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8630154 0.92 HPGD (0.56) HPGDALDH1A1L3MBTL1LMNAMMP2
SCHEMBL1360763 0.87 HPGD (0.63) HPGDALDH1A1L3MBTL1LMNAMMP2
SCHEMBL10384605 0.85 HPGD (0.61) HPGDALDH1A1L3MBTL1LMNAMMP2
SCHEMBL14468326 0.84 HPGD (0.59) HPGDALDH1A1L3MBTL1LMNAMMP2
SCHEMBL758154 0.82 CES1 (0.56) ALDH1A1L3MBTL1POLBMAPTCES1
SCHEMBL10384767 0.81 HPGD (0.56) HPGDALDH1A1L3MBTL1LMNAMMP2
Hydrogen Sulfide SCHEMBL28239188 0.80 CES1 (0.54) ALDH1A1L3MBTL1POLBMAPTCES1
SCHEMBL7198187 0.79 CES1 (0.67) HPGDALDH1A1L3MBTL1LMNACES1
SCHEMBL725552 0.79 ALDH1A1 (0.54) HPGDALDH1A1L3MBTL1LMNAPOLB
SCHEMBL9680410 0.78 SMN1; SMN2 (0.51) HPGDALDH1A1L3MBTL1LMNAEZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670740-B1 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2011-04-27 EP disclosed
US-7534880-B2 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2009-05-19 US disclosed
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2006-11-02 US disclosed
EP-1670740-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS Lamberti Spa (IT) 2006-06-21 EP disclosed
WO-2005014515-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2005-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings CDH1, CLTA, VCL HPGD 3253/4885ALDH1A1 4625/4885L3MBTL1 4802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.