Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | STS | P08842 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993723 | 0.87 | GPR119 (0.57) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL2520399 | 0.86 | ALDH1A1 (0.55) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL4130151 | 0.85 | ALDH1A1 (0.54) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL30702478 | 0.85 | ALDH1A1 (0.54) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL34461284 | 0.85 | MMP13 (0.54) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL30702487 | 0.85 | ALDH1A1 (0.54) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL13591106 | 0.84 | ALDH1A1 (0.53) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL16657610 | 0.83 | ALDH1A1 (0.52) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL13591175 | 0.83 | ALDH1A1 (0.52) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL16657606 | 0.82 | CNR1 (0.52) | ALDH1A1NPC1MAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855449-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013179024-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-12-05 | — | — | WO | disclosed |