SCHEMBL1553736

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1553753	0.81	ADORA1 (0.61)	ADORA2AADORA1
	SCHEMBL6134640	0.78	GPR119 (0.47)	ADORA2AADORA1CDK5CDK5R1PDE3B
	SCHEMBL5451849	0.78	ADORA1 (0.64)	ADORA2AADORA1CDK5CDK5R1KDM4E
	SCHEMBL1553935	0.77	ADORA1 (0.63)	ADORA2AADORA1CDK5CDK5R1PDE3B
	SCHEMBL1553233	0.76	ADORA2A (0.62)	ADORA2AADORA1CDK5CDK5R1ALDH1A1
	SCHEMBL1554693	0.76	ADORA1 (0.45)	ADORA2AADORA1KDM4EALDH1A1ADORA2B
	SCHEMBL1554448	0.75	ADORA1 (0.52)	ADORA2AADORA1ADORA2BMAP4K4
	SCHEMBL5241771	0.74	ADORA1 (0.49)	ADORA2AADORA1CDK5CDK5R1KDM4E
	SCHEMBL13966340	0.74	USP7 (0.37)	ADORA2AADORA1CDK5CDK5R1USP7
	SCHEMBL7467727	0.72	ADORA1 (0.42)	ADORA2AADORA1KDM4EALDH1A1ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.