Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539893 | 0.84 | ACHE (0.41) | ACHECHRM2CHRM3SLC6A2SLC6A4 | |
| SCHEMBL15538825 | 0.84 | CHRM2 (0.43) | ACHECHRM2CHRM3SLC6A2SLC6A4 | |
| SCHEMBL15558242 | 0.82 | ACHE (0.40) | ACHECHRM2CHRM3SLC6A2SLC6A4 | |
| SCHEMBL15538837 | 0.80 | KDM4E (0.50) | — | |
| SCHEMBL15538277 | 0.80 | NPC1 (0.42) | CHRM2CHRM3SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL15540120 | 0.77 | SLC6A2 (0.48) | CYP2C19SLC6A2SLC6A4SLC6A3REN | |
| SCHEMBL15539532 | 0.72 | OPRD1 (0.40) | ACHECYP2C19CHRM2CHRM3SLC6A2 | |
| SCHEMBL2586563 | 0.72 | CYP2C19 (0.64) | CYP2C19SLC6A3TSHR | |
| SCHEMBL4544766 | 0.71 | CCR3 (0.59) | — | |
| SCHEMBL17282142 | 0.70 | HRH3 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | disclosed |