Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | PDE6A | P16499 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11794806 | 0.91 | TSHR (0.55) | CYP2C19TSHRCYP1A2MAPK1NR1H2 | |
| SCHEMBL25060459 | 0.89 | CYP2C19 (0.53) | CYP2C19TSHRCYP1A2MAPK1NR1H2 | |
| SCHEMBL2960872 | 0.89 | CYP2C19 (0.78) | CYP2C19TSHRCYP1A2NR1H2NR1H3 | |
| SCHEMBL5789341 | 0.88 | TSHR (0.75) | CYP2C19TSHRCYP1A2MAPK1NR1H2 | |
| SCHEMBL6621779 | 0.87 | TSHR (0.79) | CYP2C19TSHRCYP1A2MAPK1NR1H2 | |
| SCHEMBL43183 | 0.84 | TSHR (0.74) | CYP2C19TSHRCYP1A2NR1H2NR1H3 | |
| SCHEMBL22620091 | 0.82 | NR1H2 (0.60) | CYP2C19TSHRCYP1A2MAPK1NR1H2 | |
| Ammonia Solution, Strong SCHEMBL17766796 | 0.82 | CYP2C19 (0.50) | CYP2C19TSHRCYP1A2MAPK1NR1H2 | |
| SCHEMBL2011193 | 0.82 | CYP2C19 (0.69) | CYP2C19TSHRCYP1A2NR1H2NR1H3 | |
| SCHEMBL7154167 | 0.82 | CYP2C19 (0.69) | CYP2C19TSHRCYP1A2NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12421187-B2 | Dihydrofolate synthase (DHFS) inhibiting agents and methods of making and using same | WASHINGTON UNIVERISTY (US) | 2025-09-23 | — | — | US | disclosed |
| US-20230322667-A1 | DIHYDROFOLATE SYNTHASE (DHFS) INHIBITING AGENTS AND METHODS OF MAKING AND USING SAME | WASHINGTON UNIVERSITY (US) | 2023-10-12 | — | — | US | disclosed |
| US-20230322667-A1 | DIHYDROFOLATE SYNTHASE (DHFS) INHIBITING AGENTS AND METHODS OF MAKING AND USING SAME | WASHINGTON UNIVERSITY (US) | 2023-10-12 | — | — | US | disclosed |
| US-20230322667-A1 | DIHYDROFOLATE SYNTHASE (DHFS) INHIBITING AGENTS AND METHODS OF MAKING AND USING SAME | WASHINGTON UNIVERSITY (US) | 2023-10-12 | — | — | US | disclosed |
| US-11622916-B2 | Photocurable composition excellent in curing depth | SHOFU INC. (JP) | 2023-04-11 | — | — | US | disclosed |
| CN-115068347-A | Photocurable composition having excellent depth of cure | 株式会社松风 | 2022-09-20 | — | — | CN | disclosed |
| US-20220287919-A1 | PHOTOCURABLE COMPOSITION EXCELLENT IN CURING DEPTH | SHOFU INC. (JP) | 2022-09-15 | — | — | US | disclosed |
| EP-4056164-A1 | PHOTOCURABLE COMPOSITION EXCELLENT IN CURING DEPTH | Shofu Inc. (JP) | 2022-09-14 | — | — | EP | disclosed |
| WO-2022032484-A1 | PYRIDAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 北京诺诚健华医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |
| EP-3210969-B1 | KCNQ2-5 CHANNEL ACTIVATOR | ONO PHARMACEUTICAL CO (JP) | 2021-04-28 | — | — | EP | disclosed |
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | disclosed |
| US-6518268-B1 | Telomerase inhibitors and methods of their use | GERON CORPORATION | 2003-02-11 | — | — | US | disclosed |
| WO-2001002377-A9 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORP (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | disclosed |
| CN-1063182-C | New aminophenylphosphonic acid compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 2001-03-14 | — | — | CN | disclosed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |
| WO-1998031689-A1 | NOVEL MIXED BENZENE ACID DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 1998-07-23 | — | — | WO | disclosed |
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |
| CN-1145908-A | New aminophenylphosphonic acid compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 1997-03-26 | — | — | CN | disclosed |
| EP-0754693-A2 | Novel aminophenylphosphonic acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322667-A1 | DIHYDROFOLATE SYNTHASE (DHFS) INHIBITING AGENTS AND METHODS OF MAKING AND USING SAME | DHFR, DHPS, MTHFD1 | CYP2C19 2711/4885TSHR 4546/4885CYP1A2 1771/4885 |
| US-11622916-B2 | Photocurable composition excellent in curing depth | ODC1, AOC2, CCNT1 | CYP2C19 1592/4885TSHR 4023/4885CYP1A2 856/4885 |
| US-20220287919-A1 | PHOTOCURABLE COMPOSITION EXCELLENT IN CURING DEPTH | ODC1, AOC2, CCNT1 | CYP2C19 1588/4885TSHR 4012/4885CYP1A2 862/4885 |
| US-12421187-B2 | Dihydrofolate synthase (DHFS) inhibiting agents and methods of making and using same | DHFR, DHPS, MTHFD1 | CYP2C19 2711/4885TSHR 4546/4885CYP1A2 1771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.