Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539741 | 0.86 | KCNH2 (0.43) | GPR119GPR183PTGS2PTGS1 | |
| SCHEMBL15538238 | 0.83 | GPR119 (0.48) | GPR119GPR183 | |
| SCHEMBL15538188 | 0.83 | GPR119 (0.46) | GPR119GPR183PTGS2PTGS1 | |
| SCHEMBL15538548 | 0.83 | GPR119 (0.46) | GPR119GPR183PTGS2PTGS1 | |
| SCHEMBL21534611 | 0.82 | PTGS2 (0.47) | GPR119GPR183PTGS2PTGS1 | |
| SCHEMBL15539139 | 0.82 | PTGS2 (0.46) | GPR119GPR183PTGS2PTGS1 | |
| SCHEMBL389015 | 0.82 | GPR119 (0.75) | GPR119 | |
| SCHEMBL16803722 | 0.81 | GPR119 (0.48) | GPR119GPR183 | |
| SCHEMBL388606 | 0.81 | GPR119 (0.46) | GPR119GPR183PTGS2PTGS1 | |
| SCHEMBL13589518 | 0.81 | PTGS2 (0.53) | GPR119PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | disclosed |