Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15538404 | 0.86 | PTGS2 (0.44) | KCNH2PTGS2PTGS1GPR119GPR183 | |
| SCHEMBL15538841 | 0.86 | GPR119 (0.41) | KCNH2PTGS2PTGS1GPR119GPR183 | |
| SCHEMBL15538366 | 0.86 | GPR119 (0.49) | PTGS2PTGS1GPR119GPR183 | |
| SCHEMBL3986213 | 0.84 | PTGS1 (0.43) | KCNH2PTGS2PTGS1GPR119GPR183 | |
| SCHEMBL387584 | 0.84 | GPR119 (0.60) | GPR119 | |
| SCHEMBL3986348 | 0.84 | LIPE (0.44) | GPR119 | |
| SCHEMBL3982941 | 0.82 | KDM1A (0.48) | KCNH2PTGS2PTGS1 | |
| SCHEMBL3984254 | 0.82 | ACHE (0.57) | PTGS2PTGS1 | |
| SCHEMBL16803720 | 0.82 | PTGS2 (0.43) | KCNH2PTGS2PTGS1GPR119GPR183 | |
| Hydrochloric Acid SCHEMBL387125 | 0.81 | KDM1A (0.47) | KCNH2PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | disclosed |