SCHEMBL15539229

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15539227	1.00	KMT2A (0.41)	KMT2ANPC1RAB9AALDH1A1LMNA
	SCHEMBL20053618	0.92	DYRK1A (0.41)	KMT2ANPC1RAB9AALDH1A1LMNA
	SCHEMBL15540083	0.89	JAK2 (0.45)	NPC1RAB9AJAK2ALOX5APFEN1
	SCHEMBL15539342	0.89	PIK3CA (0.43)	KMT2ANPC1RAB9AALDH1A1LMNA
	SCHEMBL15538282	0.89	JAK2 (0.45)	NPC1RAB9AJAK2ALOX5APFEN1
	SCHEMBL15538285	0.89	JAK2 (0.45)	NPC1RAB9AJAK2ALOX5APFEN1
	SCHEMBL15538965	0.89	PIK3CA (0.43)	KMT2ANPC1RAB9AALDH1A1LMNA
	SCHEMBL15538969	0.89	PIK3CA (0.43)	KMT2ANPC1RAB9AALDH1A1LMNA
	SCHEMBL15539689	0.88	KMT2A (0.44)	KMT2ANPC1RAB9ASCN9A
	SCHEMBL15539687	0.88	KMT2A (0.44)	KMT2ANPC1RAB9ASCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.