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Sugi Predict / Compounds / SCHEMBL15539233

SCHEMBL15539233

SCHEMBL15539233

CC(=O)c1ccc(-c2ccc(OCC3CCN(C(=O)C4(C(F)(F)F)CCC4)CC3)cn2)cc1.CC(=O)c1ccc(-c2ccc(OCC3CCNCC3)cn2)cc1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 6/20 0.48
▸ CYP4F2 P78329 10/20 0.45
▸ CYP4A11 Q02928 10/20 0.45
▸ KDM1A O60341 2/20 0.42
▸ RBP4 P02753 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15538722 0.95 GPR119 (0.52) GPR119CYP4F2CYP4A11
SCHEMBL15539234 0.94 GPR119 (0.44) GPR119CYP4F2CYP4A11KDM1ARBP4
SCHEMBL15537989 0.85 AOC2 (0.47) GPR119
Hydrochloric Acid SCHEMBL15538381 0.82 TDP1 (0.49) GPR119CYP4F2CYP4A11KDM1ARBP4
SCHEMBL15537906 0.80 GPR119 (0.48) GPR119CYP4F2CYP4A11
SCHEMBL16803727 0.76 GPR119 (0.49) GPR119CYP4F2CYP4A11
SCHEMBL15538390 0.76 GPR119 (0.77) GPR119CYP4F2CYP4A11
SCHEMBL15537877 0.75 GPR119 (0.58) GPR119CYP4F2CYP4A11
SCHEMBL15538376 0.74 AOC2 (0.48) GPR119
SCHEMBL15538794 0.73 AOC2 (0.54) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2858986-A1 PIPERIDINE DERIVATIVES FOR GPR119 AGONIST Chong Kun Dang Pharmaceutical Corp. (KR) 2015-04-15 — — EP disclosed
WO-2013187646-A1 PIPERIDINE DERIVATIVES FOR GPR119 AGONIST CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2013-12-19 — — WO disclosed