Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.31 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31001735 | 1.00 | ALDH1A1 (0.36) | ALDH1A1GAAMEN1KMT2AALOX15 | |
| SCHEMBL1552913 | 0.71 | — | — | |
| SCHEMBL674245 | 0.71 | — | — | |
| SCHEMBL29804989 | 0.71 | — | — | |
| SCHEMBL2825005 | 0.70 | ALDH1A1 (0.34) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL31001736 | 0.68 | ALDH1A1 (0.48) | ALDH1A1GAAMEN1KMT2AALOX15 | |
| SCHEMBL255970 | 0.68 | ALDH1A1 (0.48) | ALDH1A1GAAMEN1KMT2AALOX15 | |
| SCHEMBL4014164 | 0.68 | SHMT2 (0.40) | SHMT2TSHR | |
| SCHEMBL5757843 | 0.68 | ALDH1A1 (0.50) | ALDH1A1GAAMEN1KMT2AALOX15 | |
| SCHEMBL2511410 | 0.68 | HPGD (0.40) | ALDH1A1GAAMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016128470-A1 | HERBICIDE-RESISTANT HYDROXYPHENYLPYRUVATE DIOXYGENASES | BASF SE (DE) | 2016-08-18 | — | — | WO | disclosed |
| EP-3004117-A1 | SUBSTITUTED PYRIDINE COMPOUNDS HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2016-04-13 | — | — | EP | disclosed |
| EP-2855485-A1 | SUBSTITUTED PYRIDINE COMPOUNDS HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2015-04-08 | — | — | EP | disclosed |
| WO-2014097085-A1 | HERBICIDE-METABOLIZING CYTOCHROME P450 MONOOXYGENASES | BASF SE (DE) | 2014-06-26 | — | — | WO | disclosed |
| WO-2013178585-A1 | SUBSTITUTED PYRIDINE COMPOUNDS HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2013-12-05 | — | — | WO | disclosed |