Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539672 | 0.83 | PRSS1 (0.41) | EPHX2PPARGALDH1A1SLC7A5TSHR | |
| SCHEMBL18338978 | 0.78 | ALDH1A1 (0.39) | SYKP2RY1ALDH1A1HDAC3HDAC4 | |
| SCHEMBL15540163 | 0.78 | PRSS1 (0.40) | SYKP2RY1ALDH1A1TDP1SLC6A2 | |
| SCHEMBL17617234 | 0.75 | CYP1A2 (0.58) | EPHX2PPARGALDH1A1TDP1SLC6A2 | |
| SCHEMBL13269435 | 0.74 | TDP1 (0.41) | SYKP2RY1ALDH1A1TDP1SLC6A2 | |
| SCHEMBL15653895 | 0.73 | RAB9A (0.42) | SYKP2RY1ALDH1A1TDP1SLC6A2 | |
| SCHEMBL8436634 | 0.73 | ALDH1A1 (0.60) | SYKEPHX2PPARGALDH1A1TDP1 | |
| SCHEMBL8439144 | 0.72 | CYP1A2 (0.55) | SYKEPHX2PPARGPOLBTDP1 | |
| SCHEMBL26244529 | 0.72 | HPGD (0.47) | ALDH1A1HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL29088222 | 0.72 | CA1 (0.49) | SYKALDH1A1POLBTDP1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013187533-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2013-12-19 | — | — | WO | disclosed |