Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 13/20 | 0.41 |
| ▸ | TMPRSS15 | P98073 | 13/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539583 | 0.83 | SYK (0.43) | ALDH1A1SLC7A5TSHRMAPK1L3MBTL1 | |
| SCHEMBL26244529 | 0.79 | HPGD (0.47) | HPGDALDH1A1TSHRMAPK1ATM | |
| Bromide SCHEMBL4186407 | 0.77 | GRM6 (0.37) | PRSS1TMPRSS15HPGDALDH1A1SLC7A5 | |
| SCHEMBL15539430 | 0.76 | PRSS1 (0.44) | PRSS1TMPRSS15HPGDALDH1A1TSHR | |
| SCHEMBL13269217 | 0.75 | HPGD (0.40) | PRSS1TMPRSS15HPGDALDH1A1TSHR | |
| SCHEMBL4179468 | 0.75 | HPGD (0.40) | PRSS1TMPRSS15HPGDALDH1A1TSHR | |
| SCHEMBL13141322 | 0.75 | HPGD (0.40) | PRSS1TMPRSS15HPGDALDH1A1SLC7A5 | |
| SCHEMBL18338977 | 0.74 | PRSS1 (0.53) | PRSS1TMPRSS15HPGDTSHRMAPK1 | |
| SCHEMBL8565291 | 0.74 | LMNA (0.49) | PRSS1TMPRSS15HPGDALDH1A1TSHR | |
| SCHEMBL8549434 | 0.74 | TSHR (0.44) | HPGDALDH1A1SLC7A5TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9655879-B2 | Heteroarylcarboxylic acid ester derivative | EA PHARMA CO., LTD. (JP) | 2017-05-23 | — | — | US | disclosed |
| US-20160058734-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2016-03-03 | — | — | US | disclosed |
| US-9227949-B2 | Heteroarylcarboxylic acid ester derivative | AJINOMOTO CO., INC. (JP) | 2016-01-05 | — | — | US | disclosed |
| US-9024044-B2 | Heteroarylcarboxylic acid ester derivative | AJINOMOTO CO., INC. (JP) | 2015-05-05 | — | — | US | disclosed |
| US-20150099733-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2015-04-09 | — | — | US | disclosed |
| WO-2013187533-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2013-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099733-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | DPP4, DPP9, DPP7 | PRSS1 10/4885TMPRSS15 35/4885HPGD 720/4885 |
| US-20160058734-A1 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE | DPP4, DPP9, DPP7 | PRSS1 10/4885TMPRSS15 35/4885HPGD 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.