Sugi Predict

Sugi Predict / Compounds / Bromide

Bromide

Bromide

SCHEMBL4186407

CC(C)(C)OC(=O)c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)s1.[Br-]

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRM6 O15303 1/20 0.37
▸ SLC7A5 Q01650 1/20 0.36
▸ PRSS1 P07477 4/20 0.36
▸ TMPRSS15 P98073 4/20 0.36
▸ HDAC4 P56524 2/20 0.35
▸ HDAC6 Q9UBN7 2/20 0.35
▸ HPGD P15428 3/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ ALDH1A1 P00352 3/20 0.35
▸ CTSS P25774 3/20 0.34
▸ CTSK P43235 2/20 0.34
▸ CTSL P07711 1/20 0.34
▸ CTSB P07858 1/20 0.34
▸ HDAC3 O15379 1/20 0.34
▸ HDAC1 Q13547 1/20 0.34
▸ TSHR P16473 2/20 0.33
▸ ATM Q13315 2/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL7972797 0.85 MRGPRX4 (0.42) PRSS1TMPRSS15HDAC4HDAC6HPGD
Bromide SCHEMBL11736879 0.80 KMT2A (0.41) HPGDKMT2AALDH1A1TSHRL3MBTL1
Bromide SCHEMBL15987417 0.79 TDP1 (0.45) HPGDKMT2AALDH1A1TSHRMAPK1
SCHEMBL15539672 0.77 PRSS1 (0.41) SLC7A5PRSS1TMPRSS15HPGDALDH1A1
SCHEMBL26244529 0.75 HPGD (0.47) GRM6HDAC4HDAC6HPGDKMT2A
SCHEMBL15539583 0.75 SYK (0.43) SLC7A5HDAC4HDAC6KMT2AALDH1A1
SCHEMBL13884932 0.75 GRM6 (0.38) GRM6SLC7A5PRSS1TMPRSS15HDAC4
SCHEMBL13269217 0.74 HPGD (0.40) GRM6PRSS1TMPRSS15HDAC4HDAC6
SCHEMBL13141322 0.74 HPGD (0.40) GRM6SLC7A5PRSS1TMPRSS15HDAC4
SCHEMBL4179468 0.74 HPGD (0.40) GRM6PRSS1TMPRSS15HDAC4HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2024390-B1 INSULIN DERIVATIVE NOVO NORDISK AS (DK) 2015-08-19 — — EP disclosed
US-8796205-B2 Insulin derivative NOVO NORDISK A/S (DK) 2014-08-05 — — US disclosed
US-20090105121-A1 Insulin Derivative NOVO NORDISK A/S (DK) 2009-04-23 — — US disclosed
EP-2024390-A1 INSULIN DERIVATIVE Novo Nordisk A/S (DK) 2009-02-18 — — EP disclosed
WO-2007128815-A1 INSULIN DERIVATIVE NOVO NORDISK A/S (DK) 2007-11-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105121-A1 Insulin Derivative INSR, IAPP, GPR119 GRM6 3272/4885SLC7A5 357/4885PRSS1 205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.