SCHEMBL1554040

SCHEMBL1554040

CC(C)(O)C(=O)c1ccc(Oc2ccc(C(=O)C(C)(C)N3CCOCC3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
SMN1; SMN2 Q16637 4/20 0.60
TSHR P16473 2/20 0.60
MAPK1 P28482 1/20 0.60
HRH3 Q9Y5N1 1/20 0.52
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
RAB9A P51151 1/20 0.41
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
MAPT P10636 2/20 0.39
USP2 O75604 1/20 0.39
ALOX12 P18054 1/20 0.39
LMNA P02545 2/20 0.39
NPSR1 Q6W5P4 1/20 0.38
PDE4A P27815 1/20 0.38
PDE4B Q07343 1/20 0.38
PDE4C Q08493 1/20 0.38
PDE4D Q08499 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10458813 0.94 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2TSHRMAPK1HRH3
SCHEMBL10458541 0.94 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2TSHRMAPK1HRH3
SCHEMBL1553060 0.89 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2TSHRMAPK1HRH3
SCHEMBL1553920 0.89 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2TSHRMAPK1HRH3
SCHEMBL275396 0.84 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2TSHRMAPK1HRH3
SCHEMBL1553588 0.83 ALDH1A1 (0.72) ALDH1A1SMN1; SMN2TSHRMAPK1HRH3
SCHEMBL10458115 0.83 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2TSHRMAPK1HRH3
SCHEMBL18883178 0.82 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2TSHRMAPK1HRH3
SCHEMBL4421008 0.82 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2TSHRMAPK1HRH3
SCHEMBL4496847 0.82 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2TSHRMAPK1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9187658-B2 Photopolymerizable inkjet ink, ink cartridge, and inkjet recording device RICOH COMPANY, LTD. (JP) 2015-11-17 US disclosed
US-9187658-B2 Photopolymerizable inkjet ink, ink cartridge, and inkjet recording device RICOH COMPANY, LTD. (JP) 2015-11-17 US disclosed
US-20150009265-A1 PHOTOPOLYMERIZABLE INKJET INK, INK CARTRIDGE, AND INKJET RECORDING DEVICE RICOH COMPANY, LTD. (JP) 2015-01-08 US disclosed
US-20150009265-A1 PHOTOPOLYMERIZABLE INKJET INK, INK CARTRIDGE, AND INKJET RECORDING DEVICE RICOH COMPANY, LTD. (JP) 2015-01-08 US disclosed
EP-1670740-B1 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2011-04-27 EP disclosed
US-7534880-B2 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2009-05-19 US disclosed
US-7534880-B2 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2009-05-19 US disclosed
US-7534880-B2 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2009-05-19 US disclosed
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2006-11-02 US disclosed
EP-1670740-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS Lamberti Spa (IT) 2006-06-21 EP disclosed
WO-2005014515-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2005-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings CDH1, CLTA, VCL ALDH1A1 4625/4885SMN1; SMN2 4319/4885TSHR 4435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.