SCHEMBL1553060

SCHEMBL1553060

CC(C)(C(=O)c1ccc(Oc2ccccc2)cc1)N1CCOCC1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
SMN1; SMN2 Q16637 4/20 0.60
MAPK1 P28482 2/20 0.60
TSHR P16473 1/20 0.60
HRH3 Q9Y5N1 1/20 0.52
NAAA Q02083 1/20 0.49
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
KMT2A Q03164 5/20 0.48
LMNA P02545 2/20 0.48
KDM4E B2RXH2 1/20 0.46
HTT P42858 1/20 0.46
MEN1 O00255 3/20 0.46
PARP10 Q53GL7 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
RAB9A P51151 1/20 0.43
SRD5A2 P31213 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10458813 0.94 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
SCHEMBL10458541 0.94 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
SCHEMBL1554040 0.89 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
SCHEMBL1553920 0.89 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
SCHEMBL52410 0.87 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
SCHEMBL9680992 0.86 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
SCHEMBL9679993 0.84 SMN1; SMN2 (0.65) ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
SCHEMBL10949372 0.84 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
SCHEMBL275396 0.84 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
SCHEMBL11340621 0.84 SMN1; SMN2 (0.65) ALDH1A1SMN1; SMN2MAPK1TSHRHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670740-B1 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2011-04-27 EP disclosed
US-7534880-B2 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2009-05-19 US disclosed
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2006-11-02 US disclosed
EP-1670740-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS Lamberti Spa (IT) 2006-06-21 EP disclosed
WO-2005014515-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2005-02-17 WO disclosed
US-5145885-A Morpholine compound, binders CIBA-GEIGY CORPORATION (US) 1992-09-08 US disclosed
US-4992547-A Aminoaryl ketone photoinitiators CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings CDH1, CLTA, VCL ALDH1A1 4625/4885SMN1; SMN2 4319/4885MAPK1 4176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.