Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934205 | 0.98 | KCNH2 (0.42) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL3930779 | 0.92 | GRM5 (0.42) | MAPTGRM5CHRNB2CHRNA4 | |
| SCHEMBL29187190 | 0.80 | CHRNB2 (0.65) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL9741037 | 0.79 | CHRNB2 (0.46) | MAPTGRM5CHRNB2CHRNA4 | |
| SCHEMBL5886652 | 0.78 | FFAR1 (0.63) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL29187197 | 0.78 | FFAR1 (0.51) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL5886568 | 0.78 | FFAR1 (0.51) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL3064618 | 0.77 | CHRNB2 (0.67) | KCNH2MMP2MMP12GRM5CHRNB2 | |
| SCHEMBL5654809 | 0.76 | FFAR1 (0.38) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL15921874 | 0.76 | CHRNB2 (0.64) | KCNH2FFAR1FFAR4MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110257379-B | Oligonucleotides for treating patients with muscular dystrophy | 马林生物科技有限公司 | 2023-08-11 | — | — | CN | disclosed |
| EP-3608407-A1 | OLIGONUCLEOTIDE FOR THE TREATMENT OF MUSCULAR DYSTROPHY PATIENTS | BioMarin Technologies B.V. (NL) | 2020-02-12 | — | — | EP | disclosed |
| EP-2870246-B1 | OLIGONUCLEOTIDE FOR THE TREATMENT OF MUSCULAR DYSTROPHY PATIENTS | BIOMARIN TECH BV (NL) | 2019-09-11 | — | — | EP | disclosed |
| EP-2870246-A2 | OLIGONUCLEOTIDE FOR THE TREATMENT OF MUSCULAR DYSTROPHY PATIENTS | Prosensa Technologies B.V. (NL) | 2015-05-13 | — | — | EP | disclosed |
| CN-104603271-A | Oligonucleotides for treating patients with muscular dystrophy | PROSENSA TECHNOLOGIES BV | 2015-05-06 | — | — | CN | disclosed |
| WO-2014007620-A2 | OLIGONUCLEOTIDE FOR THE TREATMENT OF MUSCULAR DYSTROPHY PATIENTS | PROSENSA TECHNOLOGIES B.V. (NL) | 2014-01-09 | — | — | WO | disclosed |