Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29187197 | 1.00 | FFAR1 (0.51) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL7166353 | 0.98 | FFAR1 (0.49) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL21623404 | 0.90 | DRD2 (0.41) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL21623413 | 0.88 | HDAC8 (0.42) | FFAR1FFAR4MMP2MMP12CYP3A4 | |
| SCHEMBL5886652 | 0.86 | FFAR1 (0.63) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL21623412 | 0.84 | HDAC8 (0.42) | FFAR1CYP3A4CYP2D6CHRNB2CHRNA4 | |
| SCHEMBL9015870 | 0.81 | FFAR1 (0.58) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL4073903 | 0.81 | FFAR1 (0.58) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL4071200 | 0.81 | FFAR1 (0.58) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL7139040 | 0.81 | FFAR1 (0.58) | FFAR1FFAR4MMP2MMP12KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105707-B2 | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds | PHARMACORE, INC. (US) | 2006-09-12 | — | — | US | disclosed |
| US-20050137402-A1 | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds | DSM N.V. (NL) | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137402-A1 | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds | NAT1, B3GNT2, NISCH | FFAR1 4642/4885FFAR4 3669/4885MMP2 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.