SCHEMBL1554501

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12709030	1.00	KCNQ3 (0.50)	KCNQ3KCNQ2KCNE1KCNQ1CES2
	SCHEMBL1554502	1.00	KCNQ3 (0.50)	KCNQ3KCNQ2KCNE1KCNQ1CES2
	SCHEMBL1553299	0.85	CYP11B1 (0.50)	KCNQ3KCNQ2CES2CES1CYP11B1
	SCHEMBL1553298	0.85	CYP11B1 (0.50)	KCNQ3KCNQ2CES2CES1CYP11B1
	SCHEMBL12709046	0.85	CYP11B1 (0.50)	KCNQ3KCNQ2CES2CES1CYP11B1
	SCHEMBL5353609	0.79	CES2 (0.50)	CES2CES1ALDH1A1TSHRSMN1; SMN2
	SCHEMBL5353608	0.79	CES2 (0.50)	CES2CES1ALDH1A1TSHRSMN1; SMN2
	SCHEMBL23832211	0.76	NAPRT (0.54)	KCNQ3KCNQ2KCNE1KCNQ1CYP11B1
	SCHEMBL16460479	0.76	KCNQ3 (0.62)	KCNQ3KCNQ2KCNE1KCNQ1CES2
	SCHEMBL1554028	0.75	CACNA1B (0.44)	CES2CES1CYP11B1CYP11B2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.