Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973540 | 0.88 | ALDH1A1 (0.58) | ALDH1A1PTPN1RIPK1CYP19A1CYP3A4 | |
| SCHEMBL38656303 | 0.88 | ALDH1A1 (0.58) | ALDH1A1PTPN1RIPK1CYP19A1CYP3A4 | |
| SCHEMBL6528998 | 0.87 | RIPK1 (0.59) | ALDH1A1PTPN1RIPK1CYP19A1CYP3A4 | |
| SCHEMBL30240111 | 0.86 | ALDH1A1 (0.59) | ALDH1A1PTPN1RIPK1CYP19A1CYP3A4 | |
| SCHEMBL15543416 | 0.85 | ALDH1A1 (0.59) | ALDH1A1PTPN1RIPK1CYP1A1CYP1A2 | |
| SCHEMBL15543697 | 0.83 | ALDH1A1 (0.56) | ALDH1A1PTPN1RIPK1CYP19A1CYP3A4 | |
| SCHEMBL1146705 | 0.76 | ALDH1A1 (1.00) | ALDH1A1PTPN1MEN1KMT2AMAPT | |
| SCHEMBL4508215 | 0.76 | ALDH1A1 (0.67) | ALDH1A1PTPN1CYP19A1CYP3A4CYP1A1 | |
| SCHEMBL31074902 | 0.76 | RIPK1 (0.49) | ALDH1A1PTPN1RIPK1CYP19A1CYP3A4 | |
| SCHEMBL30099859 | 0.76 | RIPK1 (0.49) | ALDH1A1PTPN1RIPK1CYP19A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957362-B | Method for separating anti-inflammatory active ingredients of coreopsis tinctoria | 中国科学院西北高原生物研究所 | 2023-11-10 | — | — | CN | disclosed |
| WO-2014007853-A1 | DIHYDROMYRICETIN FOR THE TREATMENT OF DISEASES AND DISORDERS OF THE GLUTAMATERGIC SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-01-09 | — | — | WO | disclosed |