SCHEMBL15545353

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15544175	0.86	CYP2C19 (0.37)	ALDH1A1CYP2C19KMT2AMEN1MAPT
	SCHEMBL15544172	0.86	CYP2C19 (0.37)	ALDH1A1CYP2C19KMT2AMEN1MAPT
	SCHEMBL17467169	0.83	CYP2C19 (0.42)	ALDH1A1CYP2C19KMT2AMEN1MAPT
	SCHEMBL17467166	0.83	CYP2C19 (0.42)	ALDH1A1CYP2C19KMT2AMEN1MAPT
	SCHEMBL26928548	0.80	ALDH1A1 (0.40)	ALDH1A1CYP2C19KMT2AMEN1MAPT
	SCHEMBL15545493	0.78	ALDH1A1 (0.45)	ALDH1A1KMT2AMEN1MAPTHTT
	SCHEMBL15545495	0.78	ALDH1A1 (0.45)	ALDH1A1KMT2AMEN1MAPTHTT
	SCHEMBL15545025	0.77	MAPT (0.36)	ALDH1A1KMT2AMEN1MAPTPOLB
	SCHEMBL3318266	0.77	CTSV (0.48)	ALDH1A1CYP2C19KMT2AMEN1MAPT
	SCHEMBL16680148	0.76	CYP2C19 (0.39)	ALDH1A1CYP2C19KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.