SCHEMBL15545779

SCHEMBL15545779

C/C(C(=O)O)=C(\F)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.38
LCK P06239 1/20 0.38
FYN P06241 1/20 0.38
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
PGGT1B P53609 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15545780 1.00 FFAR3 (0.38) FFAR3LCKFYNLMNATHRB
SCHEMBL28640407 0.84 FFAR3 (0.35) FFAR3LCKFYNTHRBFNTA
SCHEMBL15546434 0.76
SCHEMBL10604698 0.76
SCHEMBL26929225 0.76
SCHEMBL15546019 0.76
SCHEMBL8471579 0.76
SCHEMBL869357 0.76
SCHEMBL14690127 0.73 CA1 (0.36) FFAR3LCKFYN
SCHEMBL10661655 0.73 FFAR3 (0.55) FFAR3LCKFYNLMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150196585-A1 COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS AND USES THEREOF VIFOR (INTERNATIONAL) LTD. (CH) 2015-07-16 US disclosed
US-20150183908-A1 COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS AND USES THEREOF VIFOR (INTERNATIONAL) LTD. (CH) 2015-07-02 US disclosed
EP-2874633-A1 COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS Relypsa, Inc. (US) 2015-05-27 EP disclosed
WO-2014015240-A1 COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS SORBENT THERAPEUTICS, INC. (US) 2014-01-23 WO disclosed
WO-2014015244-A1 COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS SORBENT THERAPEUTICS, INC. (US) 2014-01-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150183908-A1 COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS AND USES THEREOF PICALM, ORAI1, KCNN3 FFAR3 1640/4885LCK 740/4885FYN 3328/4885
US-20150196585-A1 COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS AND USES THEREOF SSB, PARG, HLA-DRB1 FFAR3 1128/4885LCK 491/4885FYN 1370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.