SCHEMBL15547328

SCHEMBL15547328

[CH2]CCC(C=C)C=CCCCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 2/20 0.39
PTGS1 P23219 1/20 0.39
PPARG P37231 1/20 0.39
OPRK1 P41145 1/20 0.39
ALDH1A1 P00352 4/20 0.38
TSHR P16473 4/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
CYP3A4 P08684 3/20 0.37
MAPT P10636 4/20 0.32
CYP2D6 P10635 4/20 0.32
CYP1A2 P05177 4/20 0.32
CYP2C9 P11712 4/20 0.32
CYP2C19 P33261 4/20 0.32
MAPK1 P28482 3/20 0.32
TP53 P04637 3/20 0.32
GMNN O75496 2/20 0.32
LMNA P02545 2/20 0.32
GLA P06280 2/20 0.32
POLB P06746 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16581548 0.91 PTGS1 (0.38) ABCG2PTGS1PPARGOPRK1ALDH1A1
SCHEMBL28097067 0.88 ABCG2 (0.41) ABCG2PTGS1PPARGOPRK1ALDH1A1
SCHEMBL14481073 0.88 ABCG2 (0.41) ABCG2PTGS1PPARGOPRK1ALDH1A1
SCHEMBL14481074 0.88 ABCG2 (0.41) ABCG2PTGS1PPARGOPRK1ALDH1A1
SCHEMBL9104258 0.84 PPARG (0.43) ABCG2PTGS1PPARGOPRK1ALDH1A1
SCHEMBL29213523 0.82 PPARG (0.45) ABCG2PTGS1PPARGOPRK1ALDH1A1
SCHEMBL27605243 0.81 PTGS1 (0.50) ABCG2PTGS1PPARGOPRK1ALDH1A1
SCHEMBL10897479 0.76 ABCG2 (0.49) ABCG2PTGS1PPARGOPRK1ALDH1A1
SCHEMBL10897482 0.76 ABCG2 (0.49) ABCG2PTGS1PPARGOPRK1ALDH1A1
SCHEMBL31411108 0.74 PPARG (0.44) ABCG2PTGS1PPARGOPRK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130617-A1 PROCESS FOR IMPROVED OPIOID SYNTHESIS RHODES TECHNOLOGIES (US) 2023-04-27 US disclosed
CN-111454598-A Light-cured composition suitable for irradiation curing of near-infrared L ED light source and application thereof 湖北固润科技股份有限公司 2020-07-28 CN disclosed
US-10316042-B2 Process for improved opioid synthesis RHODES TECHNOLOGIES (US) 2019-06-11 US disclosed
EP-2872516-B1 PROCESS FOR IMPROVED OPIOID SYNTHESIS RHODES TECH (US) 2017-08-30 EP disclosed
US-20150315203-A1 PROCESS FOR IMPROVED OPIOID SYNTHESIS RHODES TECHNOLOGIES 2015-11-05 US disclosed
EP-2872516-A1 PROCESS FOR IMPROVED OPIOID SYNTHESIS Rhodes Technologies (US) 2015-05-20 EP disclosed
WO-2014013313-A1 PROCESS FOR IMPROVED OPIOID SYNTHESIS RHODES TECHNOLOGIES (US) 2014-01-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150315203-A1 PROCESS FOR IMPROVED OPIOID SYNTHESIS OPRK1, OPRM1, OPRD1 ABCG2 1159/4885PTGS1 193/4885PPARG 4115/4885
US-10316042-B2 Process for improved opioid synthesis OPRK1, OPRM1, OPRD1 ABCG2 1159/4885PTGS1 193/4885PPARG 4115/4885
US-20230130617-A1 PROCESS FOR IMPROVED OPIOID SYNTHESIS OPRK1, OPRM1, OPRD1 ABCG2 1551/4885PTGS1 293/4885PPARG 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.