⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166020 | 0.78 | LMNA (0.35) | — | |
| SCHEMBL11115709 | 0.76 | — | — | |
| SCHEMBL5673103 | 0.76 | — | — | |
| SCHEMBL7856491 | 0.75 | — | — | |
| SCHEMBL18458136 | 0.75 | — | — | |
| SCHEMBL15199703 | 0.75 | — | — | |
| SCHEMBL14079977 | 0.74 | — | — | |
| SCHEMBL14079979 | 0.74 | — | — | |
| SCHEMBL5176374 | 0.74 | ALOX15 (0.44) | — | |
| SCHEMBL11436554 | 0.74 | MCL1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105451746-A | Compositions comprising crosslinked cationically binding polymers | RELYPSA INC | 2016-03-30 | — | — | CN | disclosed |
| US-20150183908-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS AND USES THEREOF | VIFOR (INTERNATIONAL) LTD. (CH) | 2015-07-02 | — | — | US | disclosed |
| WO-2014015244-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS | SORBENT THERAPEUTICS, INC. (US) | 2014-01-23 | — | — | WO | disclosed |