SCHEMBL15548005

SCHEMBL15548005

O=[N+]([O-])c1ccccc1-c1ccc2c3c(n(Cc4ccccc4)c2c1)CCCC3

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 4/20 0.57
CA1 P00915 3/20 0.51
CA2 P00918 3/20 0.51
HTR6 P50406 1/20 0.46
HDAC1 Q13547 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
FABP3 P05413 1/20 0.43
MAPT P10636 2/20 0.43
KMT2A Q03164 2/20 0.43
CFTR P13569 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
MEN1 O00255 1/20 0.41
APAF1 O14727 1/20 0.41
SLC2A1 P11166 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15549306 0.92 CA1 (0.51) FABP4CA1CA2HTR6HDAC1
SCHEMBL15550226 0.82 ALDH1A1 (0.43) FABP4MAPTKMT2ASMN1; SMN2MEN1
SCHEMBL15547528 0.75 ALDH1A1 (0.43) MAPTKMT2ASMN1; SMN2MEN1
SCHEMBL6688856 0.73 FABP4 (1.00) FABP4CA1CA2HTR6HDAC1
SCHEMBL6045346 0.73 CA1 (0.94) FABP4CA1CA2HTR6HDAC1
SCHEMBL6687922 0.69 FABP4 (0.77) FABP4CA1CA2HTR6HDAC1
Acetic Acid SCHEMBL9518648 0.69 CA1 (0.78) FABP4CA1CA2HTR6HDAC1
SCHEMBL15547381 0.68 MAPT (0.54) MAPTKMT2ASMN1; SMN2MEN1
SCHEMBL3853296 0.68 CA1 (0.59) FABP4CA1CA2HTR6HDAC1
SCHEMBL7464584 0.67 CA1 (0.67) FABP4CA1CA2HTR6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014014180-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-01-23 WO disclosed
WO-2014014180-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-01-23 WO disclosed