SCHEMBL15548823

SCHEMBL15548823

CCC(=O)Oc1cccc(I)c1OC(=O)CC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.41
ALOX15 P16050 1/20 0.41
ESR1 P03372 2/20 0.40
HIF1A Q16665 2/20 0.40
ELANE P08246 1/20 0.39
KMT2A Q03164 4/20 0.39
RECQL P46063 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPK1 P28482 2/20 0.37
KDM4E B2RXH2 3/20 0.36
MEN1 O00255 1/20 0.36
PTPN1 P18031 1/20 0.36
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
LMNA P02545 1/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
ALDH1A1 P00352 1/20 0.35
DRD1 P21728 1/20 0.34
HTR2A P28223 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28832125 0.85 ACHE (0.43) ACHEALOX15ESR1HIF1AELANE
SCHEMBL15558838 0.84 KMT2A (0.56) ALOX15KMT2ARECQLSMN1; SMN2KDM4E
SCHEMBL4246889 0.84 ELANE (0.46) ACHEALOX15ESR1HIF1AELANE
SCHEMBL29435434 0.84 ELANE (0.46) ACHEALOX15ESR1HIF1AELANE
Hydrochloric Acid SCHEMBL27997324 0.83 ACHE (0.42) ACHEALOX15ESR1HIF1AELANE
SCHEMBL15548666 0.83 POLM (0.53) ALOX15KMT2ARECQLKDM4EMEN1
SCHEMBL10876869 0.83 ACHE (0.41) ACHEALOX15ESR1HIF1AELANE
SCHEMBL15548062 0.82 POLM (0.55) ALOX15KMT2ARECQLKDM4EMEN1
SCHEMBL15548042 0.82 POLM (0.55) ALOX15KMT2ARECQLKDM4EMEN1
SCHEMBL28068645 0.81 KMT2A (0.42) ACHEESR1HIF1AELANEKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9593172-B2 Ziegler-natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same INDIAN OIL CORPORATION LIMITED (IN) 2017-03-14 US claimed
US-20150152199-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME INDIAN OIL CORPORATION LIMITED (IN) 2015-06-04 US claimed
EP-2872538-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME Indian Oil Corporation Ltd (IN) 2015-05-20 EP claimed
WO-2014013401-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME INDIAN OIL CORPORATION LIMITED (IN) 2014-01-23 WO claimed
EP-3050906-B1 CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF INDIAN OIL CORP LTD (IN) 2020-07-22 EP disclosed
US-9914789-B2 Ziegler-natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same INDIAN OIL CORPORATION LIMITED (IN) 2018-03-13 US disclosed
US-9873752-B2 Catalyst process modification and polymerization thereof INDIAN OIL CORPORATION LTD. (IN) 2018-01-23 US disclosed
US-9593172-B2 Ziegler-natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same INDIAN OIL CORPORATION LIMITED (IN) 2017-03-14 US disclosed
US-20160347880-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME INDIAN OIL CORPORATION LIMITED (IN) 2016-12-01 US disclosed
EP-3050906-A1 CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF Indian Oil Corporation Limited (IN) 2016-08-03 EP disclosed
US-20160215077-A1 CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF INDIAN OIL CORPORATION LTD. (IN) 2016-07-28 US disclosed
US-20150152199-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME INDIAN OIL CORPORATION LIMITED (IN) 2015-06-04 US disclosed
EP-2872538-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME Indian Oil Corporation Ltd (IN) 2015-05-20 EP disclosed
WO-2014013401-A1 ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME INDIAN OIL CORPORATION LIMITED (IN) 2014-01-23 WO disclosed