Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | FABP7 | O15540 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29435434 | 1.00 | ELANE (0.46) | ELANEFABP7FABP3FABP5ALOX15 | |
| SCHEMBL8435546 | 0.86 | ALOX15 (0.55) | ELANEALOX15ESR1HIF1AKMT2A | |
| SCHEMBL8207207 | 0.85 | MEN1 (0.51) | FABP7FABP3FABP5ALOX15KMT2A | |
| SCHEMBL15548823 | 0.84 | ACHE (0.41) | ELANEALOX15ESR1HIF1AKMT2A | |
| SCHEMBL10876869 | 0.84 | ACHE (0.41) | ELANEALOX15ESR1HIF1AKMT2A | |
| SCHEMBL370102 | 0.82 | KMT2A (0.65) | FABP7FABP3FABP5ALOX15KMT2A | |
| SCHEMBL10601943 | 0.81 | FABP7 (0.44) | FABP7FABP3FABP5KMT2ARECQL | |
| SCHEMBL28127013 | 0.80 | FABP7 (0.41) | ELANEFABP7FABP3FABP5ESR1 | |
| SCHEMBL27546336 | 0.80 | KMT2A (0.57) | ALOX15KMT2ARECQLKDM4EMEN1 | |
| SCHEMBL30942571 | 0.80 | KMT2A (0.57) | ALOX15KMT2ARECQLKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101380317-A | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV (CN) | 2009-03-11 | — | — | CN | claimed |
| WO-2019189286-A1 | CYCLOPROPYL ETHYLENE COMPOUND AND ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME | 住友化学株式会社 | 2019-10-03 | — | — | WO | disclosed |
| US-20140044723-A1 | ANTI-PLATELET MEMBRANE GLYCOPROTEIN VI MONOCLONAL ANTIBODY | MOCHIDA PHARM CO LTD (JP) | 2014-02-13 | — | — | US | disclosed |
| US-8524870-B2 | Anti-platelet membrane glycoprotein VI monoclonal antibody | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2013-09-03 | — | — | US | disclosed |
| US-20130095120-A1 | ANTI-PLATELET MEMBRANE GLYCOPROTEIN VI MONOCLONAL ANTIBODY | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2013-04-18 | — | — | US | disclosed |
| US-8389692-B2 | Anti-platelet membrane glycoprotein VI monoclonal antibody | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-05 | — | — | US | disclosed |
| EP-1876240-B1 | ANTI-HUMAN PLATELET MEMBRANE GLYCOPROTEIN VI MONOCLONAL ANTIBODY | MOCHIDA PHARM CO LTD (JP) | 2012-08-22 | — | — | EP | disclosed |
| CN-101380317-B | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV PHARMACEUTICAL CO LTD | 2010-12-08 | — | — | CN | disclosed |
| US-20090092612-A1 | ANTI-PLATELET MEMBRANE GLYCOPROTEIN VI MONOCLONAL ANTIBODY | MOCHIDA PHARMACEUTICAL CO. LTD. | 2009-04-09 | — | — | US | disclosed |
| CN-101380317-A | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV (CN) | 2009-03-11 | — | — | CN | disclosed |
| EP-1876240-A1 | ANTI-PLATELET MEMBRANE GLYCOPROTEIN VI MONOCLONAL ANTIBODY | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2008-01-09 | — | — | EP | disclosed |
| CN-1140519-C | Trifluoromethylbiphenglyl-dihalophenylazolines as pesticides | �����ɷ� | 2004-03-03 | — | — | CN | disclosed |
| CN-1279675-A | Trifluoromethylbiphenyl-dihalophenylazolines as pesticides | NOVARTIS AG (CH) | 2001-01-10 | — | — | CN | disclosed |
| CN-1046711-C | Unsaturated hydroxyalkyl quinoline carboxylic acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1999-11-24 | — | — | CN | disclosed |
| US-5206178-A | Complexing to polymer; immobilization to solid | GENETIC SYSTEMS CORPORATION (US) | 1993-04-27 | — | — | US | disclosed |
| CN-1061407-A | Unsaturated hydroxyalkyl quinoline carboxylic acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1992-05-27 | — | — | CN | disclosed |
| EP-0268296-B1 | MEMBRANE AFFINITY CONCENTRATION IMMUNOASSAY | GENETIC SYSTEMS CORPORATION (US) | 1992-04-22 | — | — | EP | disclosed |
| EP-0268296-A2 | Membrane affinity concentration immunoassay | GENETIC SYSTEMS CORPORATION (US) | 1988-05-25 | — | — | EP | disclosed |