Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246889 | 0.84 | ELANE (0.46) | ACHEALOX15ESR1HIF1AELANE | |
| SCHEMBL67780 | 0.84 | ALOX15 (0.50) | ACHEALOX15ESR1HIF1AELANE | |
| SCHEMBL29435434 | 0.84 | ELANE (0.46) | ACHEALOX15ESR1HIF1AELANE | |
| SCHEMBL15548823 | 0.83 | ACHE (0.41) | ACHEALOX15ESR1HIF1AELANE | |
| SCHEMBL26153367 | 0.81 | ACHE (0.47) | ACHEALOX15ESR1HIF1AELANE | |
| SCHEMBL27622102 | 0.80 | CA12 (0.39) | ACHEELANEKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL27853104 | 0.79 | ACHE (0.41) | ACHEALOX15ESR1HIF1AELANE | |
| SCHEMBL27534597 | 0.79 | ESR1 (0.44) | ACHEALOX15ESR1HIF1AELANE | |
| SCHEMBL10876865 | 0.79 | CA12 (0.41) | ACHEALOX15ESR1HIF1AELANE | |
| SCHEMBL29484682 | 0.78 | HIF1A (0.52) | ACHEALOX15ESR1HIF1AGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071640-B1 | NON-A, NON-B HEPATITIS VIRUS | CONNAUGHT LABORATORIES INCORPORATED (US) | 1986-06-04 | — | — | EP | disclosed |