Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837956 | 0.90 | CA2 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL1554757 | 0.88 | ALDH1A1 (0.35) | ALDH1A1KDM4ELMNA | |
| SCHEMBL38660120 | 0.84 | ALDH1A1 (0.38) | ALDH1A1KDM4E | |
| Nitric Acid SCHEMBL8525731 | 0.83 | CA2 (0.41) | ALDH1A1 | |
| SCHEMBL10935741 | 0.79 | TSHR (0.46) | ALDH1A1KDM4ELMNA | |
| SCHEMBL28086990 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNA | |
| SCHEMBL3273563 | 0.72 | — | — | |
| SCHEMBL11042921 | 0.72 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNA | |
| Nitric Acid SCHEMBL2006085 | 0.71 | ALDH1A1 (0.35) | ALDH1A1KDM4ELMNA | |
| Nitric Acid SCHEMBL1979549 | 0.71 | ALDH1A1 (0.35) | ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8692031-B2 | Method for preparing polyamine compounds | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-04-08 | — | — | US | disclosed |
| US-8692031-B2 | Method for preparing polyamine compounds | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-04-08 | — | — | US | disclosed |
| EP-2464621-B1 | METHOD FOR PREPARING POLYAMINE COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-05 | — | — | EP | disclosed |
| EP-2464621-B1 | METHOD FOR PREPARING POLYAMINE COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-05 | — | — | EP | disclosed |
| US-20120202934-A1 | METHOD FOR PREPARING POLYAMINE COMPOUNDS | ADVANCION CORPORATION | 2012-08-09 | — | — | US | disclosed |
| US-20120202934-A1 | METHOD FOR PREPARING POLYAMINE COMPOUNDS | ADVANCION CORPORATION | 2012-08-09 | — | — | US | disclosed |
| US-20120202934-A1 | METHOD FOR PREPARING POLYAMINE COMPOUNDS | ADVANCION CORPORATION | 2012-08-09 | — | — | US | disclosed |
| EP-2464621-A1 | METHOD FOR PREPARING POLYAMINE COMPOUNDS | Dow Global Technologies LLC (US) | 2012-06-20 | — | — | EP | disclosed |
| WO-2011044478-A1 | METHOD FOR PREPARING POLYAMINE COMPOUNDS | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2011-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202934-A1 | METHOD FOR PREPARING POLYAMINE COMPOUNDS | SRM, C5, PRMT5 | ALDH1A1 2921/4885KDM4E 193/4885LMNA 1555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.