Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TERT | O14746 | 3/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | FABP4 | P15090 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2215864 | 0.86 | FAAH (0.56) | FAAHCYP1A2CYP2C19KMT2ASOAT1 | |
| SCHEMBL2218313 | 0.86 | FAAH (0.56) | FAAHCYP1A2CYP2C19KMT2ASOAT1 | |
| SCHEMBL29246353 | 0.86 | FAAH (0.56) | FAAHCYP1A2CYP2C19KMT2ASOAT1 | |
| SCHEMBL11330189 | 0.84 | FAAH (0.61) | FAAHCYP1A2CYP2C19KMT2ASOAT1 | |
| SCHEMBL25836769 | 0.83 | FAAH (0.65) | FAAHCYP1A2CYP2C19KMT2ASOAT1 | |
| SCHEMBL5507749 | 0.83 | FAAH (0.65) | FAAHCYP1A2CYP2C19KMT2ASOAT1 | |
| SCHEMBL16245390 | 0.83 | FAAH (0.59) | FAAHCYP1A2CYP2C19KMT2ASOAT1 | |
| SCHEMBL2216417 | 0.82 | KDM4E (0.59) | FAAHCYP1A2CYP2C19KMT2ASOAT1 | |
| SCHEMBL2048630 | 0.82 | FAAH (0.67) | FAAHCYP1A2CYP2C19KMT2ASOAT1 | |
| SCHEMBL2937979 | 0.82 | FAAH (0.67) | FAAHCYP1A2CYP2C19KMT2ASOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150202179-A1 | FATTY ACID DERIVATIVES FOR USE IN A METHOD OF TREATING DEPRESSION AND ASSOCIATED CONDITIONS | YISSUM RES DEV CO (IL) | 2015-07-23 | — | — | US | claimed |
| US-20150202179-A1 | FATTY ACID DERIVATIVES FOR USE IN A METHOD OF TREATING DEPRESSION AND ASSOCIATED CONDITIONS | YISSUM RES DEV CO (IL) | 2015-07-23 | — | — | US | disclosed |
| WO-2014013497-A1 | FATTY ACID DERIVATIVES FOR USE IN A METHOD OF TREATING DEPRESSION AND ASSOCIATED CONDITIONS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2014-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150202179-A1 | FATTY ACID DERIVATIVES FOR USE IN A METHOD OF TREATING DEPRESSION AND ASSOCIATED CONDITIONS | ALOX5, FFAR2, FASN | FAAH 10/4885CYP1A2 904/4885CYP2C19 477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.