Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 19/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15549845 | 0.84 | CYP26A1 (0.69) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4280917 | 0.76 | CYP26A1 (1.00) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4283358 | 0.70 | CYP26A1 (1.00) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20067360 | 0.67 | ALDH1A1 (0.53) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10144151 | 0.62 | FABP4 (0.62) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29688279 | 0.62 | ALDH1A1 (0.68) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1923372 | 0.62 | ALDH1A1 (0.68) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28146064 | 0.61 | ALDH1A1 (0.80) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9054852 | 0.60 | CYP26A1 (0.42) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5583199 | 0.60 | RAB9A (0.53) | CYP1A2CYP3A4CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160038490-A1 | COMPOSITIONS AND METHODS FOR TREATING DYSPROLIFERATIVE DISEASES | ANGION BIOMEDICA CORP. (US) | 2016-02-11 | — | — | US | claimed |
| WO-2014015137-A2 | COMPOSITIONS AND METHODS FOR TREATING DYSPROLIFERATIVE DISEASES | ANGION BIOMEDICA CORP. (US) | 2014-01-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160038490-A1 | COMPOSITIONS AND METHODS FOR TREATING DYSPROLIFERATIVE DISEASES | DUSP6, CYP26B1, CYP26A1 | CYP26A1 3/4885CYP1A2 165/4885CYP3A4 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.