Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15564169 | 0.93 | DAO (0.57) | DAOMAPTTDP1KDM4ENPC1 | |
| SCHEMBL16968245 | 0.93 | DAO (0.57) | DAOMAPTTDP1KDM4ENPC1 | |
| SCHEMBL15565204 | 0.85 | DAO (0.50) | DAOKMT2AGRIA1GRIA2GRIA4 | |
| SCHEMBL15564747 | 0.84 | DAO (0.49) | DAOMAPTKDM4EKMT2AGRIA1 | |
| SCHEMBL15563883 | 0.81 | DAO (0.52) | DAOKDM4EKMT2AGRIA1GRIA2 | |
| SCHEMBL15565105 | 0.81 | DAO (0.56) | DAOMAPTKMT2AGRIA1GRIA2 | |
| SCHEMBL15564035 | 0.81 | DAO (0.56) | DAOMAPTKMT2ANPBWR1ALDH1A1 | |
| SCHEMBL16968259 | 0.78 | DAO (0.56) | DAOMAPTKMT2AGRIA1GRIA2 | |
| SCHEMBL15565182 | 0.78 | DAO (0.58) | DAO | |
| SCHEMBL15565149 | 0.78 | DAO (0.58) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014025993-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-02-13 | — | — | WO | disclosed |